Description
Rederm Pharmacodynamics
Rederm is a combination drug containing the active substances betamethasone dipropionate and salicylic acid.
Betamethasone dipropionate – a synthetic fluorinated glucocorticosteroid (GKS) – has anti-inflammatory, antipruritic and vasoconstrictive effects.
Salicylic acid, having keratolytic effect, promotes penetration of betamethasone into the skin. It has a bacteriostatic and some fungicidal action.
The combined effect of the active ingredients leads to a rapid reduction in symptoms such as itching, irritation, erythema and pain.
Indications
Reduction of inflammatory manifestations of dry and hyperkeratic dermatoses sensitive to GCS therapy, including psoriasis, chronic atopic dermatitis, neurodermitis, lichen planus, eczema (including montiform eczema, eczema of the hands, eczematous dermatitis), dyshydrosis, seborrheic dermatitis of the scalp, ichthyosis and other ichthyoid-like conditions
Contraindications
– Hypersensitivity to betamethasone, salicylic acid and other ingredients of the drug.
– Pink acne, acne, perioral dermatitis.
– Bacterial, viral or fungal skin infections.
– Trophic ulcers due to chronic venous insufficiency, wounds.
– Skin tumors.
– Post-vaccination skin reactions.
– Perianal and genital itching.
– Children under the age of 2 years.
– Pregnancy (long-term treatment in high doses).
– Period of breast-feeding.
Caution
Children under 12 years of age, hepatic insufficiency, long-term treatment, use on large areas of skin, use of occlusive dressings.
Use during pregnancy and lactation
Pregnancy
The safety of using glucocorticosteroids when applied to the skin has not been established. During pregnancy the drug use is possible if the potential benefit to the mother exceeds the possible risk to the fetus or child. Topical glucocorticosteroids should not be used in high doses or for prolonged periods of time during pregnancy. Consult your doctor before using Rederm® if you are pregnant or think you may be pregnant or are planning to become pregnant. Breastfeeding period
Since it is not yet known whether the systemic absorption level of topical glucocorticosteroids is sufficient to show detectable concentrations in the mother’s milk, either breastfeeding or use of the drug should be discontinued, considering how necessary it is for the mother. Consult a physician before using Rederm®.
Directions for use and dosages
- Externally.
- Apply a thin layer of the drug to the skin lesions twice a day (morning and night).
- In some patients the maintenance effect can be achieved by less frequent applications.
- Children aged 2 to 12 years – Apply a thin layer 1 or 2 times a day for not more than 5 days.
- The course of treatment should not exceed 3 weeks.
- The duration of treatment, specific treatment regimen, repeated courses of treatment should be agreed with your doctor.
- Use the drug only in accordance with the method of administration and in those doses that are listed in the instructions for use.
- If necessary, please consult your doctor before using the drug.
