Description
NEXT ACTIVEGEL Pharmacodynamics
NEXT ACTIVEGEL is a combination of two active substances – ibuprofen and levomenthol.
Ibuprofen is a non-steroidal anti-inflammatory agent, a derivative of propionic acid, non-selectively blocks cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) enzymes, thus inhibiting the synthesis of prostaglandins – mediators of pain, inflammation and hyperthermia. When used topically, ibuprofen has analgesic, anti-inflammatory and anti-edema effects (reduces exudation and edema due to inflammation).
Levomenthol has a local irritant effect, which determines the rapid development of the analgesic effect of the drug.
The combination of ibuprofen and levomenthol reduces pain and inflammation, is effective for pain in the joints when moving and at rest, reduces morning stiffness of the joints.
Indications
As a local anesthetic and anti-inflammatory agent for conditions such as muscle pain, back pain, arthritis, pain from ligament injuries and sprains, sports injuries and neuralgia.
Contraindications
Hypersensitivity to ibuprofen or other components of the drug;
– Hypersensitivity to acetylsalicylic acid and other NSAIDs;
– complete or incomplete combination of bronchial asthma, recurrent nasal and paranasal sinus polyposis and intolerance to acetylsalicylic acid or other NSAIDs (including history);
– skin integrity disorders at the application site (including infected wounds and abrasions, sore throat dermatitis, eczema);
– children under 14 years of age;
– Pregnancy, lactation.
Dosage and administration
- The drug is intended for external use.
- Adults and children over 14 years a small amount of gel (3-5 cm long strip) is applied thinly to the skin over the lesion and rubbed gently.
- Immediately after application of the drug it is necessary to wash hands, if they are not the object of treatment.
- Reapplication of the drug is possible not earlier than 4 hours later. The drug may be applied up to 4 times within 24 hours.
- Duration of using the drug without consulting a doctor is not more than 10 days. If longer use is necessary, you should consult a doctor.
