Description
Nazik Pharmacodynamics
Xylometazoline belongs to a group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes narrowing of blood vessels of nasal mucosa, restores nasal passageway, facilitates nasal breathing. The action of the drug usually comes within a few minutes after application and lasts up to 10 hours.
Dexpanthenol is a B vitamin – a derivative of pantothenic acid. Dexpanthenol converts in the body into pantothenic acid, which is part of coenzyme A and is involved in acetylation processes, carbohydrate and fat metabolism, the synthesis of acetylcholine, corticosteroids, porphyrins, stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, metabolic and mild anti-inflammatory effect.
Indications
It is used for acute respiratory diseases with rhinitis symptoms, acute allergic rhinitis, vasomotor rhinitis, sinusitis, otitis media (as a part of combined therapy to reduce nasopharyngeal mucosa edema), to facilitate rhinoscopy, restoration of impaired nasal breathing after surgical interventions in the nasal cavity.
Contraindications
Hypersensitivity to the components of the drug, arterial hypertension, tachycardia, marked atherosclerosis, hyperthyroidism, glaucoma, atrophic rhinitis, dry rhinitis, porphyria, prostatic hyperplasia, surgical operations on the meninges (in anamnesis), simultaneous use with monoamine oxidase inhibitors (MAO) and tricyclic antidepressants, children under 2 years of age.
Caution
Diabetes mellitus, pheochromocytoma, diseases of the cardiovascular system (including coronary heart disease), hypersensitivity to the action of adrenergic drugs, accompanied by insomnia, dizziness, arrhythmias, tremors, increased blood pressure.
Administration during pregnancy and lactation
The drug should not be used during pregnancy. It is necessary to avoid application of the drug during lactation.
Directions for use and dosages
- Intranasally.
- For children from 2 to 6 years of age.
When using a vial with a pump dosing device, packed separately. - Remove the pump dosing device from the package. Open the bottle with the drug, screw the dispensing device on the neck of the bottle, remove the protective cap. The bottle is ready to use.
- Before the first use of the spray, press the pump dispenser several times until an even spray pattern appears.
- When using a bottle with an integrated pump dispenser.
- Remove the protective cap from the integrated pump dispenser. The bottle is ready to use.
- Before using the spray for the first time, press the integrated pump dispenser several times until an even spray pattern appears. When using the spray, the bottle must be held upright.
- During the injection you should inhale lightly with your nose. One injection into each nasal passage 3-4 times a day. The duration of therapy is 5-7 days.
- Do not use for more than 7 days. Duration of drug administration in children is set after consultation with a physician.
- Repeated use is possible only after a break of several days. If after 5 days of treatment no improvement occurs or symptoms worsen or new symptoms appear, consult a doctor.
- Use the drug only according to the indications, the method of administration and in the doses specified in the instructions.
