Description
Tilaxin Pharmacodynamics
Low-molecular synthetic inducer of interferon, stimulating formation in the body of all types of interferon (alpha, beta, gamma and lambda). The main producers of interferon in response to tiloron administration are intestinal epithelial cells, hepatocytes, T lymphocytes, neutrophils and granulocytes. After oral administration the maximum production of interferon is determined in the sequence intestine – liver – blood in 4-24 hours.
Tiloron has immunomodulatory and antiviral effects.
In human leukocytes it induces synthesis of interferon. It stimulates bone marrow stem cells, and, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. Effective against various viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpes simplex viruses. The mechanism of antiviral action is associated with inhibition of translation of virus-specific proteins in infected cells, resulting in suppression of virus reproduction.
Indications
Treatment of influenza and other acute respiratory infections, treatment of herpetic infection.
Prevention of influenza and other acute respiratory viral infections.
Contraindications
– Hypersensitivity to tiloron and other components of the drug;
– Pregnancy and breast-feeding;
– Children under 18 years of age.
Usage during pregnancy and lactation
The drug is contraindicated in pregnancy and during breast-feeding.
Dosage and administration
- Tiloron is used orally, after meals.
- For the treatment of flu and other acute respiratory viral infections – 125 mg per day for the first two days of treatment, then 125 mg after 48 hours. For a course of 750 mg. For the prevention of flu and other acute respiratory viral infections – 125 mg once a week for 6 weeks. For a course of 750 mg.
- For the treatment of herpetic infection – the first two days with 125 mg, then after 48 hours with 125 mg. The course dose is 1.25 g to 2.5 g. When treating influenza and other acute respiratory infections, if symptoms persist for more than 4 days, consult a physician.
