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Terbinafine (Termicon) cream 1% – [15 g tube]

$12.42

Antifungal agent for external use

SKU: 62910 Category:

Description

Termicon cream Pharmacodynamics
Antifungal drug for external use, which has a broad spectrum of antifungal activity. In low concentrations, terbinafine has fungicidal effect against dermatophytes (Trychophyton rubrum, T.mentagrophytes, T.verrucosum, T.violaceum, T. tonsurans, Microsporum canis, Epidermophyton floccosum), molds (e.g. Aspergillus, Cladosporium, Scorpulariopsis brevicalius), certain dimorphs (Pityrosporum orbiculare) and yeasts (mainly candida albicans). Activity against the remaining yeast fungi Candida spp. may be fungicidal or fungistatic, depending on their species.
Terbinafine specifically alters the early stage of sterol biosynthesis occurring in fungi. This leads to ergosterol deficiency and intracellular accumulation of squalene, which causes cell death of the fungus. Terbinafine acts by inhibiting the squaleneepoxidase enzyme located on the cell membrane of the fungus.
Terbinafine has no effect on the cytochrome P450 system in humans and therefore on the metabolism of hormones or other drugs.

Indications
Prevention and treatment of fungal skin infections, including:
– Mycoses of the feet (“fungus” of the foot);
– inguinal epidermophytosis;
– Fungal lesions of smooth skin of the body;
– Infections caused by yeast-like fungi of the genus Candida (candida), particularly diaper rash;
– Ringworm (pityriasis).

Contraindications
Hypersensitivity to terbinafine or to any component of the drug; breast-feeding period, children under 12 years of age (for this dosage form).
With caution: hepatic and/or renal failure, alcoholism, suppression of bone marrow hematopoiesis, tumors, metabolic diseases, vascular occlusive disease of the extremities.
Use in pregnancy and during breast-feeding
In experimental studies terbinafine properties have not been revealed. To date, no malformations have been reported on the use of terbinafine cream.
However, because clinical experience with the use of terbinafine cream in pregnant women is very limited, it should not be used unless absolutely necessary. In pregnancy, it is used only if the anticipated benefit to the mother exceeds the potential risk to the fetus. A physician should be consulted.
Terbinafine is excreted with breast milk, therefore the drug should not be used in nursing mothers. Infants should not be allowed to come into contact with any skin surface treated with the cream.

Dosage and administration

  • Externally.
  • Adults and children over 12 years: Before applying the cream to clean and dry the affected areas. The cream is applied 1 or 2 times a day, a thin layer on the affected skin and adjacent areas and lightly rubbing. In infections accompanied by diaper rash (under the breasts, between the fingers, between the buttocks, groin area), the place of application of the cream can be covered with gauze, especially at night.
  • Average duration and number of applications
  • Dermatomycosis of the feet 1 week 1 time a day
  • Dermatomycosis of trunk, shins, folds 1 week once a day
  • Cutaneous candidiasis 1 or 2 weeks 1 or 2 times a day
  • Lichen mosaic 2 weeks 1 or 2 times a day
  • A decrease in the severity of clinical manifestations is usually noticed in the first days of treatment. In case of irregular treatment or its premature termination there is a risk of recurrent infection.
  • Regimen of drug dosing in elderly patients does not differ from the described above.
  • Administration of the drug in children. It is not recommended to use this drug in children younger than 12 years old.
  • If after treatment no improvement occurs or new symptoms appear, consult your physician.
  • Use the drug only according to the method of use and in such doses as specified in the instructions. If necessary, please consult your doctor before using the medicine.