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Sea buckthorn extract (Hiporhamin) sublingual 20 mg – [20 tablets]


Herbal antiviral agent

SKU: 61379 Category:


Hyporamine Pharmacodynamics
Hyporamine ® is a dry purified extract from the leaves of sea buckthorn (Hippophae rhamnoides L.) family Elaeagnaceae, which is a polyphenol complex galloellagotannins, whose biologically active components are hydrolysable tannins that have common structural elements in the form of glucosogalloyl and hexahydroxyphenoyl residues.
Hyporamine® has high antiviral activity against various strains – influenza A and B viruses, adenoviruses, paramyxoviruses, herpes simplex viruses, shingles, cytomegalovirus (CMV), respiratory syncytial virus (PC-virus), human immunodeficiency virus (HIV infection). Inhibitory effect of the drug on virus reproduction is manifested at early stages of their development. One of the mechanisms of action of the drug is inhibitory effect on viral neuraminidase.
Hyporamine® induces production of interferon in blood cells in in vitro experiments and increases interferon content in blood of patients.
The drug also has a moderate antimicrobial effect against Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa), Mycobacterium tuberculosis, Candida albicans and some mycella fungi (Microsporum canis) in in vitro experiments.
Hyporamine® is low toxic. It has no allergizing, immunotoxic, mutagenic, teratogenic and carcinogenic properties.

Hyporamine® is used in adults and children as therapeutic and prophylactic agent against influenza (A and B), parainfluenza, PC-virus, adenovirus and other acute respiratory viral infections; Angina, passing against acute respiratory viral diseases (complex therapy); with acute and relapsing forms of herpes simplex extragenital and genital localization, with shingles, varicella and CMV-infection.

Hypersensitivity to the drug components. Children under 3 years of age (taking into account the solid dosage form of the tablet). Sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.
With caution:
Diabetes mellitus.
Pregnancy and lactation:
During pregnancy and lactation the drug may be used if the estimated benefit to the mother is greater than the potential risk to the fetus and child.

Directions for use and dosages.

  • Treatment. Hyporamine® tablets 1 tablet (20 mg) is kept in oral cavity until complete resorption. Adults and children over 12 years old are prescribed 1 tablet (20 mg) 4-6 times daily, children 6-12 years old – 1 tablet (20 mg) 3-4 times daily, children 3-6 years old – 1/2 tablet (10 mg) 2-4 times daily.
  • Duration of use – from 3 days to 3 weeks, depending on the nosological form of the disease. If flu – at least 3 days; if parainfluenza, PC-viral, adenoviral infections, angina, occurring against acute respiratory viral diseases (complex therapy), and other ARI – at least 5 days.
  • In chicken pox, shingles, herpesvirus and CMV infections, the duration of treatment depends on the severity of the process and is 3-10 days for mild forms of the disease. In severe and recurrent forms of the disease the minimum course of treatment is 2-3 weeks.
  • Repeated courses of treatment are advisable.
  • For prophylaxis during outbreak of influenza Hyporamine® tablets are taken according to age dosage from 3 days to 3 weeks.
  • As a prophylactic agent to prevent the development of viral complications (herpesvirus diseases and CMV infection) in immunosuppressive therapy in postoperative patients in risk groups, Hyporamine® tablets (20 mg) are used 3 times a day for 5-7 days.