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Rimantadine 50 mg – [20 tablets]

$12.42

Antiviral agent

SKU: 62695 Category:

Description

Rimantadine Pharmacodynamics
Rimantadine is active against various strains of influenza A virus.
Being a weak base, rimantadine acts by increasing the pH of endosomes, the membrane-containing vacuoles that surround the viral particles after they enter the cell. Preventing acidification in these vacuoles blocks the fusion of the viral envelope with the endosome membrane, thus preventing the transfer of viral genetic material into the cell cytoplasm. Rimantadine also inhibits the exit of viral particles from the cell, i.e. it interrupts the transcription of the viral genome.

Indications
Prophylaxis and early treatment of influenza A in adults and children over 7 years of age.

Contraindications
– Acute liver diseases;
– Acute and chronic kidney disease;
– thyrotoxicosis;
– Hypersensitivity to rimantadine;
– Pregnancy and breast-feeding;
– children under 7 years of age;
– in lactose deficiency, lactose intolerance, glucose-galactose malabsorption (because the drug contains lactose).
With caution:
Arterial hypertension, atherosclerosis of cerebral vessels, liver failure, epilepsy, diseases of the gastrointestinal tract.
Pregnancy and lactation:
Rimantadine is contraindicated during pregnancy and breastfeeding.

Dosage and administration

  • Inside, after a meal, with water.
  • Treatment of influenza should be started within 24-48 hours after the appearance of disease symptoms.
  • On the first day, adults are prescribed 100 mg 3 times a day, on the second and third days – 100 mg 2 times a day, on the fourth and fifth days – 100 mg once a day. On the first day of the disease it is possible to use the drug once in a dose of 300 mg.
  • Children aged 7 to 10 years are prescribed 50 mg 2 times a day, 11 to 14 years – 50 mg 3 times a day. Over 14 years old – doses for adults. It is taken for 5 days.
  • For flu prevention, adults are prescribed 50 mg once a day for up to 30 days.
  • Children over 7 years of age – 50 mg once a day for 15 days.