Description
Uroprost-D Pharmacodynamics
The drug has anti-inflammatory and anti-aggregation action, stimulates the muscles of the bladder.
Active substances of the prostate extract belong to a group of peptide bioregulators – cytomedines. These drug substances are peptides with a molecular weight of 1 to 10 kDa. Low molecular weight peptides are paraa or autocrine in nature and act as transs pecific intra- and intercellular messengers.
Prostate peptides reduce blood clotting time and increase antiaggregation activity of the vascular wall, improve blood microcirculation, enhance blood fibrinolytic activity, increase contractile activity of detrusor myocytes in vivo, in vitro.
They have immunomodulatory and immunostimulatory effects, enhance synthesis of antihistamine and antiserotonin antibodies.
At the heart of the application of peptide bioregulators in the treatment of chronic prostatitis is the ability of these drugs to restore microcirculation, have an indirect anti-inflammatory effect by increasing the synthesis of antihistamine and antiserotonin antibodies, as well as their immunomodulatory and immunostimulatory effects.
Treatment of benign prostatic hyperplasia is based on the most important biological effect of cytomedines: organotropicity, which allows to regulate the processes of differentiation and function of cells in the organ from which they are isolated.
Indications
Chronic abacterial prostatitis, conditions before and after operations on the prostate, benign prostatic hyperplasia.
Contraindications .
Individual intolerance (including hypersensitivity in the history).
Dosage and administration
- The drug is used rectally after defecation or purging enema. Soaked suppository with water, put it deep into the anus.
- Apply 1 suppository 2 times a day (morning and evening). After the drug is injected, it is desirable for the patient to stay in bed for 30-40 minutes.
- Duration of treatment – 5-10 days. Repeated courses are possible under indications; it is recommended not earlier than 2-4 weeks.
