Description
Sialor Rhino Pharmacodynamics
Oxymetazoline belongs to the group of alpha-adrenergic stimulants for local use. It has a vasoconstrictor effect. When administered intranasally, it reduces swelling of the mucous membrane of the upper airways, which relieves nasal breathing and opens the mouths of the sinuses and eustachian tubes. The action of the drug is seen 5 minutes after application and lasts for 8-12 hours.
Indications
Treatment of acute respiratory diseases accompanied by a runny nose;
allergic rhinitis;
vasomotor rhinitis;
Restoration of drainage in inflammation of paranasal sinuses, eustachitis, otitis media;
To eliminate swelling before diagnostic manipulations in the nasal passages.
Contraindications
Hypersensitivity to the drug components;
atrophic (dry) rhinitis;
intake of monoamine oxidase inhibitors during the previous 2 weeks and within 2 weeks after their withdrawal;
closed-angle glaucoma;
Condition after transsphenoidal pituitaryectomy;
Children under 1 year of age – for 0.025% drops;
children under 6 years of age – for 0.05% drops;
pregnancy;
period of lactation.
Caution
In patients suffering from cardiovascular diseases (arterial hypertension, coronary heart disease, chronic heart failure, tachycardia, arrhythmias), carbohydrate metabolism disorders (diabetes), thyroid disorders (hyperthyroidism), pheochromocytoma, chronic renal failure, prostatic hyperplasia (urinary retention) and those taking tricyclic antidepressants and bromocriptine.
Administration during pregnancy and lactation
The drug should be used only after a careful assessment of the relation between the risks and benefits for the mother and the fetus.
Dosage and administration method
- Intranasally.
- Adults and children over 6 years of age: use – 1-2 drops of 0.05% solution in each nasal passage 2 – 3 times a day.
- Children of 1 to 6 years of age – use 1-2 drops of 0.025% solution in each nostril 2-3 times a day.
- Children under 1 year of age up to 4 weeks of age are prescribed 1 drop of 0.01 % solution in each nostril 2-3 times a day. From the 5th week of life and up to 1 year of age – 1-2 drops in each nostril 2-3 times a day.
- Do not use the drug for more than 7 days. If the drug is used frequently and for a long time, the feeling of “stuffy” nose may appear again or worsen. If these symptoms occur, stop treatment and consult a doctor.
