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Olopatadine (Oloridin) eye drops 0.1% – [5 ml vial]


Antiallergic drug for local use in ophthalmology. H1-histamine receptor blocker

SKU: 62314 Category:


Oloridin Pharmacodynamics
Olopatadine is a potent selective anti-allergic/antihistamine drug whose pharmacological effects are developed through several different mechanisms of action.
It is an antagonist of histamine (the main mediator of allergic reactions in humans) and prevents histamine-induced release of inflammatory cytokines in conjunctival epithelial cells.
In vitro studies suggest inhibition of proinflammatory mediator release by conjunctival mast cells.
In patients with nasolacrimal ducts patency, local application of olopatadine in the form of instillations into the conjunctival sac reduced the severity of nasal symptoms often accompanying seasonal allergic conjunctivitis.
Olopatadine has no clinically significant effect on pupil diameter.

Treatment of symptoms of seasonal allergic conjunctivitis.

Hypersensitivity to the components of the drug, pregnancy and lactation, age less than 3 years.
In patients with concomitant “dry” eye syndrome and corneal diseases.
Use during pregnancy and breastfeeding
No studies have been conducted on the effect of topical application of olopatadine in ophthalmology on human fertility.
There are no or limited data on topical use of olopatadine in ophthalmology in pregnant women. Animal studies have obtained data on the toxic effects of olopatadine on reproductive function when used systemically. The use of olopatadine during pregnancy and women of childbearing age who do not use contraception is not recommended.
Breast-feeding period
Excretion of olopatadine into breast milk has been observed when using the drug in animals. The risk for newborns and infants cannot be excluded. It is not recommended to use the drug during breast feeding.

Directions for use and dosages

  • Topically.
  • One drop of the solution is put into conjunctival sac of the affected eye twice a day (8 hours apart).
  • Duration of treatment shall be up to four months.
  • If necessary, the drug may be used in combination with other drugs. In this case, the interval between their application should be at least 5 minutes.
  • Elderly people
  • There is no need to adjust the dosage for elderly patients.
  • Children over 3 years of age.
    The drug may be used in the same doses as in adults.
  • Renal or hepatic impairment
    No studies have been conducted on patients with renal or hepatic impairment regarding the administration of olopatadine in the form of eye drops. However, no dose adjustments are expected to be necessary in patients with renal or hepatic impairment.
  • Procedure for handling the vial:
    1. Rotate the vial counterclockwise to open it and remove the cap. 2.
    Carefully, without touching the tip of the vial with your fingers, turn the vial upside down, fix it between thumb and forefinger of one hand.
    3. Tilt your head back, place the tip of the vial over your eye and with the index finger of your other hand pull down the lower eyelid. Slightly press the bottle and drip the desired amount of drug into the conjunctival sac of the eye.
    Avoid contact of the tip of the open vial with the surface of the eye and hands.
    4. After use place the cap on the vial and close by rotating it clockwise.
    After opening the bottle the drug can be used within 1 month. At the end of this period the drug should be thrown away.
  • Do not use the drug if the vial is visibly damaged.