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Ofloxacin (Lafrax) eye or ear drops 0.3% – [5 ml vial]


Antibacterial drug of the fluoroquinolone group for topical use in ophthalmology and ent practice

SKU: 61839 Category:


Lafrax Pharmacodynamics
A broad-spectrum antimicrobial of the group of fluoroquinolones, it acts on the bacterial enzyme DNA-gyrease, which provides superspiralization and thus stability of DNA bacteria (destabilization of DNA chains leads to their death). It has a bactericidal effect. It is active against beta-lactamase-producing microorganisms and fast-growing atypical mycobacteria. Sensitive: Staphylococcus aureus (including strains), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, Corynebacterium spp, Micrococcus spp, Bacillus spp, Enterobacteriaceae (Escherichia coli, Citrobacter, Enterobacter spp, Klebsiela spp, Proteus spp., Salmonella spp., Serratia spp., Shigella spp.), Pseudomonas aeruginosa and Pseudomonas species, Haemophilus influenza, Haemophilus ducreyi, Branhamella catarhalis, Neisseria gonorrhoeae, Neisseria menengitidis, Acinetobacter spp, Campylobacter spp., Gardenerella vaginalis, Helicobacter pylori, Brucella spp. The drug also shows activity against Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma pneumoniae and some other mycoplasmas.
Clostridium species, Bacteroides species and Peptococcus species are resistant. The resistance of Pseudomonas aeruginosa varies between 15-20% and the resistance of Staphylococcus aureus between 5-10%.

Bacterial infections of the anterior eye caused by Ofloxacin-sensitive microorganisms in adults and children 1 year of age and older: corneal ulcers, conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, blepharoconjunctivitis, dacryocystitis, meibomitis (barley), chlamydial eye infections; prophylaxis and treatment of bacterial infection after eye injuries and surgical procedures.
Ear infections.
Lafrax is indicated for the treatment of bacterial infections caused by pathogens susceptible to Ofloxacin in adults and children 12 years of age and older:
– external otitis media, chronic purulent media otitis media, including with perforation of the tympanic membrane;
– Prevention of infectious complications during surgical interventions in adults;
– external otitis media and acute media otitis media with a tympanostomy tube inserted in children from 1 to 11 years of age.
The official recommendations on the use of antibacterial drugs should be taken into account.

– Hypersensitivity to the components of the drug and other quinolone derivatives;
– non-bacterial diseases of the appendages of the eye, anterior and posterior segment of the eye;
– non-bacterial otitis media;
– Children (under 1 year of age);
– Pregnancy, breast-feeding.
With caution
– childhood.
Administration during pregnancy and breast-feeding
Contraindicated use during pregnancy and breast-feeding.

Dosage and administration

  • Topically.
  • Infectious eye diseases.
  • The drug is drop into the conjunctival sac of the diseased eye 2-4 times a day. It is not recommended to use the drug for more than 2 weeks.
  • Ear infections
  • Adults and children over 12 years of age
  • Frequency of drug administration and duration of treatment shall be determined by the doctor individually.
  • As a rule, in case of otitis externa 10 drops are put into the affected ear 2 times a day for 10 days.
  • In the treatment of chronic suppurative otitis media with chronic perforation of the tympanic membrane, the recommended dosage is 10 drops in the affected ear
    2 times a day for 14 days.
  • Children from 1 to 11 years of age
  • Frequency of drug administration and duration of treatment shall be determined by a doctor individually.
  • For treatment of external otitis media and acute otitis media with a tympanostomy tube inserted the recommended dosage is 5 drops in the affected ear 2 times a day for 10 days.
  • Before instillation the bottle should be warmed in the hand for 1-2 minutes to avoid dizziness (possible with a cold solution). The instillation is done while the patient is lying on his side. After instillation the patient should remain in this position for 5 minutes to facilitate passage of the solution through the external auditory canal. If it is necessary to instill in the other ear, proceed in the same way.