Meldonium-Organic 500 mg – [60 capsules]

Description

Meldonium-Organica Pharmacodynamics
Meldonium is a precursor of carnitine, the structural analogue of gamma-butyrobetaine (GBB), a substance found in every cell of the human body.
Under conditions of increased stress, meldonium restores the balance between cellular oxygen supply and demand, eliminates the accumulation of toxic metabolic products in cells, protecting them from damage, and has a tonic effect.
Its use increases the body’s resistance to stress and its ability to quickly restore energy reserves.
The drug has a stimulating effect on the central nervous system (CNS), increasing motor activity and physical endurance. Thanks to these properties, Meldonium is used for increasing physical and mental performance.

Indications
In the treatment of coronary heart disease (angina, myocardial infarction), chronic heart failure and dyshormonal cardiomyopathy, and in the treatment of subacute and chronic cerebrovascular disorders (post-stroke, cerebrovascular insufficiency).
Withdrawal syndrome in chronic alcoholism (in combination with specific therapy).
Reduced performance, mental and physical overload (including in athletes).
The drug may give positive results during doping control (see section “Special indications”).

Contraindications
Hypersensitivity to meldonium or any other drug component.
Increased intracranial pressure (due to venous outflow disorders and intracranial tumors).
Pregnancy and the period of breastfeeding.
Age under 18 years (safety has not been confirmed).
With caution:
In cases of liver and/or kidney disease.
Pregnancy and lactation:
The safety of use in pregnant women has not been studied, therefore, in order to avoid possible adverse effects on the fetus, the use of the drug in pregnant women is contraindicated.
Excretion with milk and effect on the health of the newborn have not been studied; therefore, if it is necessary to use the drug, breastfeeding should be stopped.

Dosage and administration

• Because of the possible development of the excitatory effect, it is recommended to use in the first half of the day and not later than 17:00 when taking several times a day.
• Coronary heart disease (angina, myocardial infarction), chronic heart failure and dyshormonal cardiomyopathy:
• As part of the complex therapy of 500 – 1000 mg per day orally, applying the entire dose at once or dividing it into 2 times. Course of treatment: 4-6 weeks.
• Dyshormonal cardiomyopathy – in the complex therapy of 500 mg orally, per day. The course of treatment: 12 days.
• Subacute and chronic cerebral blood disorders (after a stroke, cerebrovascular failure).
  As part of complex therapy after the end of the course of injection therapy with Mildonium Organica, the drug continues to be taken orally at 500-1000 mg per day, using the entire dose at once or dividing it into 2 times. Course of treatment: 4-6 weeks.
• In chronic disorders – as part of the complex therapy of 500 mg orally per day. Total course of treatment: 4-6 weeks.
• Repeated courses (usually 2-3 times a year) are possible after consultation with the doctor.
• Reduced performance, mental and physical overload (including athletes).
  Adults – inside 500 mg, 2 times a day. The course of treatment: 10-14 days.
• If necessary, treatment should be repeated in 2-3 weeks.
  Athletes 500-1000 mg orally 2 times a day before training.
• Course duration in the preparatory period of training: 14-21 days, during the competition period: 10-14 days.
• Withdrawal syndrome in chronic alcoholism (in combination with specific therapy).
• By mouth 500 mg 4 times a day. Course of treatment: 7-10 days.