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Gentamicin sulfate, dexpanthenol, mometasone furoate (Tetraderm) cream – [30 g tube]


Anti-inflammatory, antibacterial, antifungal and regenerating agent for external use

SKU: 62921 Category:


Tetraderm Pharmacodynamics
The combined preparation for external use.
It has anti-inflammatory, antipruritic, antiexsudative, antibacterial, antifungal (fungicidal) and regenerating effect. The activity of the drug is due to the pharmacological properties of its constituent components.
A broad-spectrum antibiotic of the aminoglycoside group. It acts bactericidally and provides highly effective external treatment of primary and secondary bacterial skin infections.
Active against Gram-negative microorganisms: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; Gram-positive microorganisms: Staphylococcus aureus (coagulase positive, coagulase negative and some strains producing penicillinase).
Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid is a water-soluble B vitamin (vitamin B5) – a component of coenzyme A. It stimulates skin regeneration, normalizes cell metabolism, accelerates mitosis and increases the strength of collagen fibers. An increased need for pantothenic acid can be observed in case of skin or tissue damage, and its deficiency can be compensated by external application of dexpanthenol. It penetrates into all layers of the skin. It has a regenerating, mild anti-inflammatory effect.
A synthetic glucocorticosteroid (GCS) that has local anti-inflammatory, antipruritic and anti-exudative effects. GCS induce the release of phospholipase A2 inhibitory proteins collectively known as lipocortins, which control the biosynthesis of inflammatory mediators such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.
Econazole is a synthetic imidazole derivative. It has antifungal and antibacterial effects. Inhibits the biosynthesis of ergosterol, which regulates the permeability of the cell wall of microorganisms. Easily soluble in lipids and well penetrates into tissues.
It is active against dermatophytes Trichophyton, Microsporum, Epidermophyton, yeast-like fungi of the genus Candida, Corynebacterium minutissimum as well as Malassezia furfur (Pityrosporum orbiculare) causing shingles and some gram-positive bacteria (streptococci, staphylococci).


Treatment of dermatoses of inflammatory genesis with concomitant bacterial and mycotic infection or with high probability of secondary infection (simple and allergic dermatitis, atopic dermatitis (including diffuse neurodermitis), limited neurodermitis, eczema, dermatomycoses (dermatophytosis, candidiasis, herpes zoster), especially if localized in the groin area and large skin folds; simple chronic herpes (limited neurodermitis).


– Hypersensitivity to dexpanthenol, econazole, gentamicin, mometazone or any of the ingredients of the drug;
– Cutaneous postvaccination reactions;
– skin tuberculosis;
– cutaneous manifestations of syphilis;
– varicella pox;
– herpes simplex;
– application in the area of open wounds;
– pink acne;
– perioral dermatitis;
– Children under 18 years of age (efficacy and safety have not been established).
– Pregnancy and period of breastfeeding;
– Use on large areas of skin;
– prolonged use;
– Use when the skin integrity is compromised;
– When using occlusive dressings.


Directions for use and dosages


  • Externally.
  • The cream is applied to the affected skin areas in a thin layer, gently rubbing, 2 times a day until a positive clinical result.
  • Duration of treatment is individual, depends on the size, localization of the lesion and the severity of the disease and is usually 1-2 weeks. With dermatomycosis of the feet the average duration of treatment is 2-4 weeks. It is not recommended to use Tetraderm® for more than 4 weeks.
  • If no improvement or new symptoms appear after treatment, consult a doctor. Use the drug only according to the way of use and in such doses as stated in the instructions. If necessary, please consult your doctor before using the medicinal product.