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Description
Zinocap cream Pharmacodynamics
Zinc pyrithione has anti-inflammatory, antibacterial and antifungal activity. Antibacterial activity of zinc pyrithione is shown against a number of Gram-positive and Gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.) Zinc pyrithione reduces intracellular ATP level, promotes depolarization of cell membranes, causing death of fungi and bacteria. Antifungal activity is especially pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare) causing inflammation and excessive flaking in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action is not studied.
Indications
– psoriasis
– Atopic dermatitis (eczema, neurodermatitis)
– seborrheic dermatitis
– dry skin
Contraindications .
Hypersensitivity, children under 1 year of age.
Dosage and administration
- Zinocap is intended for external use.
- Used in adults and children from 1 year.
- The cream is applied in a thin layer on the affected area 2-3 times a day.
- Duration of treatment for:
- – Psoriasis – 1-1.5 months, repeated courses – when signs of exacerbation;
- – Atopic dermatitis – 3-4 weeks;
- – Seborrheic dermatitis – 2 weeks.
