Description
Diclofenac-Acrihin Pharmacodynamics
The active ingredient diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with pronounced analgesic and anti-inflammatory properties. By indiscriminately inhibiting cyclooxygenase type 1 and 2, it disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.
Diclofenac-Acri is used to eliminate pain syndrome and reduce swelling associated with inflammation. When used topically, it relieves or eliminates joint pain at rest and on the move. It reduces morning stiffness and swelling of joints, helps to increase range of motion.
Indications
– Post-traumatic inflammation of soft tissues and joints, e.g. due to sprains, strains and contusions;
– Rheumatic soft tissue diseases (tendovaginitis, bursitis, periarticular lesions)
– Pain syndrome and swelling associated with diseases of the muscles and joints (rheumatoid arthritis, osteoarthritis, radiculitis, lumbago, sciatica, muscle pain of rheumatic and non-rheumatic origin).
Contraindications
– Anamnestic data about the attack of bronchoobstruction, rhinitis, urticaria after taking acetylsalicylic acid or other NSAIDs;
– Pregnancy (III trimester);
– lactation period;
– Children under 6 years of age;
– skin integrity disorders;
– Hypersensitivity to diclofenac or other components of the drug, to acetylsalicylic acid or other NSAIDs.
Caution
Hepatic porphyria (acute condition), gastrointestinal erosive lesions, severe liver and kidney function abnormalities, chronic heart failure, elderly age, bronchial asthma, pregnancy (I and II trimester).
Administration during pregnancy and lactation
The drug should not be used in III trimester of pregnancy. There is no experience of using the drug during lactation. Use in the I and II trimesters is possible only after consultation with the doctor.
Dosage and administration method.
- Outwardly. It is applied 3-4 times per day in adults and children over 12 years old in a thin layer over inflammation and it is gently rubbed in. The required amount of drug depends on the size of the painful area. A single dose of the drug is 2-4 g (by volume it is comparable with the size of a large cherry).
- After applying the drug hands should be washed.
- Duration of treatment depends on the indication and the observed effect. After 2 weeks of using the drug you should consult your doctor.
