Description
Skynoclear Pharmacodynamics
Causes moderate cytostatic effect (at the expense of inhibition of cell proteins synthesis), manifested in normalization of keratinization processes in the wall of sebaceous glands follicles; Has antimicrobial action (first of all, in relation to Propionibacterium acnes and Staphylococcus epidermidis) both on the surface of skin and in sebaceous glands, as well as anti-inflammatory effect (decreasing neutrophil granulocytes metabolism and production of free radical oxygen forms – important factors of inflammatory process maintenance)
Prolonged use of the drug does not form resistance of micro-organisms.
Azelaic acid dose-dependently inhibits the growth and viability of abnormal melanocytes. The therapeutic effect in hyperpigmentation (melasma) is due to inhibition of DNA synthesis and/or suppression of cellular respiration of abnormal melanocytes.
Indications
– Common acne (acne vulgaris);
– Rosacea
Contraindications
– Hypersensitivity to azelaic acid and other ingredients of the drug;
– Children under 12 years of age.
Use during pregnancy and lactation:
In pregnancy and during breastfeeding, the drug should be used only if the anticipated benefit to the mother exceeds the possible risk to the fetus and child. It is necessary to avoid applying the cream on mammary gland area before lactation.
Directions for use and dosages
- Outwardly.
- Maximum duration of therapy depends on the individual disease pattern and the severity of symptoms.
- Adults and children over 12 years old gel is applied evenly in a thin layer 2 times / day. (morning and evening) on previously cleansed (soft cleansers and water) and dried skin areas of the face and, if necessary, the neck and upper chest, affected by acne.
- About 2.5 cm of the gel column is sufficient for the entire surface of the face.
- The drug should be used regularly during the entire course of treatment, the duration of which depends on the severity of the disease.
- In patients with common acne (acne vulgaris) a marked improvement is usually observed after 4 weeks. For best results, the drug should be continued for several months.
- If symptoms persist, it is advisable to consult a doctor.
