Description
Rinostein Pharmacodynamics
Mucolytic and vasoconstrictor action of the drug is a reflection of the pharmacological properties of the active substances included in its composition.
Acetylcysteine has mucolytic activity due to free sulfhydryl group, which by breaking disulfide bonds of mucus glycoproteins has a thinner effect on nasopharyngeal secretion.
Tuaminoheptane sulfate is a sympathomimetic amine, when used topically it has a vasoconstrictor effect without systemic effects.
These two substances act synergistically to reduce intranasal resistance.
Indications
Acute and subacute rhinitis with thick pus-mucous secretion, chronic rhinitis, vasomotor rhinitis, atrophic rhinitis, sinusitis.
Contraindications
– Hypersensitivity to the active substances or any of the excipients.
– Cardiovascular disease, including hypertension.
– Cerebrovascular diseases in the history, including the presence of relevant risk factors (due to alpha-sympathomimetic activity).
– A history of seizures.
– Pheochromocytoma.
– Closed-angle glaucoma.
– Concomitant administration of other nasal sympathomimetic agents, including other nasal congestion agents.
– Patients who are currently receiving or have received monoamine oxidase inhibitors A (RIMA) for 2 weeks.
– Hypophysectomy or surgery with dura mater exposure.
– Children younger than 6 years of age.
Dosage and administration
- The drug is injected into the nasal cavity as a spray with a spray nozzle.
- Adults: 2 spray doses (2 spray nozzle presses) in each nostril 3-4 times a day.
- Children over 6 years of age: 1 spray (1 spray nozzle press) in each nostril 3-4 times a day.
- Duration of treatment should not exceed 7 days. Do not exceed the recommended doses and course of treatment without consulting a doctor.
- Instructions for use of nasal spray
1. open the bottle by unscrewing the spray nozzle. 2.
2. Open the ampoule by pressing on the break ring or dot and notch located on the head of the ampoule.
3. Pour the preparation from the ampoule into the bottle.
4. Screw the spray nozzle onto the bottle.
5. Remove the cap from the spray nozzle. 6.
6. Activate the spray nozzle by holding the bottle vertically upwards with a few pushes.
7. Pour the desired amount of product into the nasal cavity by pressing the spray nozzle.
8. Place the cap on the spray nozzle.
9. Mark the date of opening of the ampoule with the drug on the tracking label, and stick the tracking label on the bottle (if it is not glued, but placed in the package).
- The drug can be used within 20 days from the date of opening. After this period of time, the drug should be discarded.
