Description
Streptocid Soluble Pharmacodynamics
Antimicrobial bacteriostatic agent, sulfonamide. Mechanism of action of the drug is due to competitive antagonism with paraaminobenzoic acid (PABA), inhibition of dihydropteroate synthase, disruption of synthesis of tetrahydrofolic acid, required for synthesis of purines and pyrimidines. Active against Staphylococcus spp., Streptococcus spp. including S.pyogenes, S.pneumoniae, Legionella spp., Brucella spp., Escherichia coli, Shigella spp., Klebsiella spp., Proteus spp., Salmonella spp, Serratia spp., Calymmatobacterium granulomatis, Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Nocardia asteroids, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp.
When applied to the skin, it promotes rapid healing of wounds and epithelialization of erosions.
Indications
Infected wounds of different etiology, burns (I-II degree), folliculitis, furuncles, carbuncles, acne, impetigo, rye and other purulent-inflammatory skin processes.
Contraindications .
Hypersensitivity to the components of the drug, anemia, renal/liver failure, congenital deficiency of glucose-6-phosphate dehydrogenase, azotemia, porphyria, pregnancy, lactation.
Caution
Children under 3 months of age.
Dosage and administration
- Outwardly. Liniment is applied to the gauze bandage, which is put on the affected area, and bandaging is done every 1-2 days.
- If affected area is large, daily liniment dosage in terms of mesulfamide should not exceed 6 g in adults (120 g liniment), 0.6 g in children under 1 year old (12 g liniment), 1.8 g in children 1-5 years old (36 g liniment), 3 g in children 5-12 years old (60 g liniment).
- The course of treatment is 10-14 days.
