Bifidobacterium bifidum (Probifor) oral 500000000 CFU – [6 sachets]

BIOLOGICAL PROPERTIES

Antidiarrheal action of the drug is due to the high concentration of bifidobacteria (Bifidobacterium bifidum № 1) sorbed on particles of activated charcoal, which are antagonists of a wide range of pathogenic (shigella, salmonella, Staphylococcus aureus, etc.) and conditionally pathogenic microorganisms (protists, Klebsiella etc.).

Antiinfective effect of the drug is enhanced by sorption of bifidobacteria on charcoal particles which leads to accelerated normalization of gastrointestinal tract microbiocenosis, activation of restorative processes in mucous membranes and increased anti-infective resistance of the body.

Antitoxic effect of the drug is achieved by rapid repopulation of the intestine microcolony bifidobacteria, the restoration of normal microflora, which prevents the penetration of toxins in the internal environment of the body and, as a natural biosorbent, accumulates a significant amount of toxic substances coming from outside or formed in the body

Bifidobacteria at high concentrations activate intestinal parietal digestion, synthesis of vitamins and amino acids, increase the protective function of the intestine and the body’s immune defense.

– Diarrhea of various etiologies;

– food toxic infections;

– Acute intestinal infections of bacterial and viral nature (salmonellosis, shigellosis, enterocolitis, caused by pathogenic Enterobacteriaceae or staphylococcus aureus, rotavirus infection), or unspecified etiology;

– Dysbacteriosis of various etiologies, including those developed against the background of and after taking antibiotics, cytostatic, radiation therapy; complicating the course of viral hepatitis, cirrhosis of the liver, intestinal diverticulosis of various localizations;

– Newborns (including prematurely born) children with a burdened premorbid background, starting from the period of stay in the maternity hospital, to improve the adaptation period, as well as with pronounced dysbacteriosis;

– pregnant women in preparation for childbirth, cesarean section and in the postoperative period.

The drug is used in the treatment of

– Chronic infectious and non-specific inflammatory diseases of the digestive tract (gastroduodenitis, pancreatitis, proctosigmoiditis, colitis, including ulcerative colitis);

– patients (including newborns) with secondary immunodeficiency states, with severe infectious-inflammatory and purulent-septic diseases (sepsis, peritonitis, etc.); with skin diseases (atopic dermatitis, streptoderma, eczema);

– Irritable bowel syndrome, other functional intestinal disorders;

– Syndrome of impaired intestinal absorption of various etiologies;

– Acute respiratory viral infections and influenza;

– surgical patients (including trauma) for preoperative preparation and prevention of postoperative complications; in postgastroresection disorders and conditions after cholecystectomy;

– cancer patients during chemotherapy, radiation therapy, before and after surgery.

Contraindications .

Congenital lactase deficiency. Impaired glucose-galactose absorption.

 

• In acute intestinal infections, food poisoning, diarrhea:
• – Children under 6 months 1 sachet 2 times a day, children over 6 months 1 sachet 3-4 times a day (possible with short intervals of 2-3 hours), the course of 2-3 days, when clinical symptoms persist, treatment is lengthened to 4-5 days;
• – Children over 7 years of age and adults 2-3 sachets 2 times a day, a course of 3-5 days;
• – Adults to stop diarrhea in the early stages of the disease – 3 sachets 2 times a day with an interval of 30 minutes to 1 hour; the drug can be increased to 6 sachets at a time, once a day, a course of 1 to 3 days
• In chronic diseases of the gastrointestinal tract and functional intestinal disorders – children and adults once 3 packages at evening meals, adults – perhaps 2 packages 2 times a day. The course of treatment 5-15 days. With a serious course of the disease the drug can be increased in children and adults from 1 year to 6 packets per day, and the course to increase to 30 days.
• Dysbacteriosis of various etiologies, chronic intestinal infections, patients with immunodeficiency disorders, skin diseases, and to improve the course of the period of adaptation in infants:
• – Premature infants 1 bag 1-2 times a day;
• – Premature infants and children under 3 years old – 1 sachet 2 times a day;
• – Children from 3 to 7 years – 1 sachet 3 times a day;
• – Children over 7 years of age and adults – 2-3 bags – 2 times a day. The course of treatment 7-10 days.
• In the complex treatment of acute respiratory viral infections and influenza patients of all age groups are used from 1-2 days of the disease in one bag 3 times a day. The course of treatment is 2 days.
• Surgical patients, pregnant women in preparation for cesarean section in order to reduce postoperative complications:
• – Before surgery, 1 bag 3 times a day for 2-3 days; persons suffering from intestinal dysbacteriosis, who received antibiotics and chemopreparations, preoperative course is extended to 7 days;
• – From 2-7 days after surgery, 1 sachet 3 times a day for 2-3 days, when indicated – 7-10 days.
• Probifor® take during meals, if necessary, regardless of the meal.  The drug is mixed with liquid food, preferably fermented dairy products, newborns and infants – with breast milk or formula for artificial feeding. The drug can be mixed with 30-50 ml of boiled water at room temperature, which creates a turbid suspension with black sorbent particles. The resulting aqueous suspension should be drunk without achieving complete dissolution.