Description
Corvalol Neo Pharmacodynamics
A combined preparation, the action of which is caused by the properties of its constituent substances. It has sedative and antispasmodic effects, moderate cardiotonic effect (slows rhythm and increases strength of heart contractions), has moderate hypotensive properties.
Ethylbromisovalerianate
Ethylbromizovalerianat possesses sedative and antispasmodic effect caused by irritation mainly of receptors in oral cavity and nasopharynx, decreased reflex excitability in central nervous system sections and increased inhibition in cortex and subcortical brain structures, as well as decreased activity of central vasomotor centers and direct local spasmolytic effect on smooth musculature. The nature of the action is similar to that of valerian drugs.
Motherwort herb
Motherwort herb has a marked sedative effect (sedative), moderately lowers the frequency and increases the force of heart contractions, exhibits moderate hypotensive properties.
Peppermint oil
Peppermint oil has a reflex vasodilatory, antispasmodic, mild choleretic, antiseptic. The mechanism of action is related to the ability to irritate the “cold” receptors of the mucous membrane of the mouth and expand reflexively mainly vessels of the heart and brain. It eliminates the phenomena of flatulence by irritating the mucous membrane receptors of the gastrointestinal tract (GIT), increasing intestinal peristalsis.
Diphenhydramine
Diphenhydramine is a first generation blocker of H1-histamine receptors. Its action on the central system is due to blockade of the brain’s H1-histamine m-cholinoreceptor receptors. It reduces or prevents histamine-induced smooth muscle spasms, increased capillary permeability, tissue edema, itching and hyperemia, has antiemetic and sedative effects, and has a sedative effect. Antagonism with histamine is shown more in relation to local vascular reactions than to systemic ones, i.e. reduction of blood pressure.
Indications
Increased nervous irritability, as a sedative in sleep disorders not associated with organic disorders of the central nervous system; neurasthenia
Contraindications
– Hypersensitivity to the drug components;
– Severe renal and/or hepatic impairment;
– closed-angle glaucoma;
– prostatic hyperplasia;
– bladder neck stenosis;
– bronchial asthma;
– epilepsy;
– pregnancy;
– period of lactation (breastfeeding);
– Children under 18 years of age (efficacy and safety not established);
– porphyria;
– pyloroduodenal stenosis;
– Erosive ulcerative lesions of the gastrointestinal tract (acute phase);
– stenotic peptic ulcer disease of the stomach and duodenum.
Dosage and administration
- Is the inside, before a meal, 3 times a day for 30 drops, pre-dissolved in a small amount (30-40 ml) of water.
- Shake the bottle before use.
- The course of treatment 10-15 days.
- According to a doctor’s recommendation may be repeated course of treatment, but not earlier than 1 month.
