Description
Potassium Iodide Pharmacodynamics
Iodine refers to essential micronutrients. Without iodine is impossible to normal functioning of the thyroid gland, because it is part of the thyroxine and triiodothyronine. Thyroid hormones are involved in the development of all organs and systems, in the regulation of metabolic processes in the body: protein, fat, carbohydrate and energy, they also regulate the activity of the brain, nervous and cardiovascular system, mammary glands, growth and development of children, the formation of its intellectual abilities. Iodine deficiency is especially dangerous for children, adolescents, pregnant and lactating women.
Potassium iodide, being a source of iodine, fills its shortage in the body, prevents the development of iodine deficiency diseases, prevents the development of goitre associated with iodine deficiency in food; normalizes the size of the thyroid gland in newborns, children, adolescents and adults.
Indications
– Prevention of iodine deficiency disorders, including endemic goiter (especially pregnant and lactating women);
– Prevention of goiter recurrence after surgical removal or after goiter treatment with thyroid hormones;
– Treatment of diffuse euthyroid goiter in newborns, children, adolescents and young adults.
Contraindications
– hyperthyroidism;
– Subclinical hyperthyroidism with iodine doses greater than 150 mcg per day;
– Duhring’s dermatitis herpetiformis;
– solitary toxic thyroid adenomas and functional thyroid autonomy (focal and diffuse), nodular toxic goiter (except for preoperative therapy for thyroid blockade);
– Hypersensitivity to iodine.
Potassium iodide should not be taken in hypothyroidism, except when the development of the latter is caused by severe iodine deficiency.
Administration of the drug should be avoided during radioactive iodine therapy, in the presence or suspicion of thyroid cancer.
Because the drug contains lactose monohydrate, it is not recommended for patients with rare hereditary diseases associated with galactose intolerance, lactase deficiency or glucose-galactose malabsorption.
Pregnancy and lactation:
During pregnancy and breastfeeding, the need for iodine increases, so it is especially important to use potassium iodide in sufficient doses to ensure adequate intake of iodine in the body. The drug penetrates the placenta and is excreted with breast milk. If a nursing woman takes potassium iodide, additional prescription of the drug is not required for breastfed infants.
Administration of the drug during pregnancy and during breast-feeding is possible only in the recommended doses.
During therapy, it is necessary to take into account the amount of iodine taken with food.
How to use and doses
- In determining the required dose of the drug should take into account regional and individual characteristics of the intake of iodine in food.
- This is especially important when prescribing the drug to infants and children under 4 years of age.
- Prevention of iodine deficiency diseases:
Newborns and children: 50-100 mcg of iodine per day (1/2 to 1 tablet of potassium iodide 100 mcg);
Adolescents and adults: 100-200 mcg iodine per day (1 tablet of Potassium Iodide 100 mcg or 1 tablet of Potassium Iodide 200 mcg);
During pregnancy and breastfeeding: 100-200 mcg iodine per day (1 tablet of Potassium Iodide 100 mcg or 1 tablet of Potassium Iodide 200 mcg. - Prevention of goiter recurrence after surgical removal or after completing goiter treatment with thyroid hormones:
100-200 mcg of iodine daily (1 tablet of potassium iodide 100 mcg or 1 tablet of potassium iodide 200 mcg). - Treatment of euthyroid goiter:
Infants and children: 100-200 mcg iodine per day (1 tablet of Potassium Iodide 100 mcg or 1 tablet of Potassium Iodide 200 mcg);
Adolescents and adults of young age: 200 mcg iodine per day (2 tablets of potassium iodide 100 mcg or 1 tablet of potassium iodide 200 mcg). - The daily dose of the drug should be taken in one course, after meals, with plenty of fluids. When prescribing the drug to infants and children under 3 years of age, it is recommended to dissolve the tablet in a small amount (1 tablespoon) of boiled water at room temperature.
- Usually the drug is used for preventive purposes for several months or years, and often for the whole life.
- For treatment of goiter in newborns in most cases 2-4 weeks is enough; in children, adolescents and adults 6-12 months or more is usually required. The length of treatment is determined by the doctor.
