Description
Xyloct-Solopharm Pharmacodynamics
Xylometazoline belongs to a group of local vasoconstrictors (decongestants) with alpha2-adrenomimetic action. It has a fast, pronounced and prolonged vasoconstrictor effect on the vessels of the nasal cavity mucosa, thus eliminating its swelling and hyperemia. It restores nasal passageway patency and facilitates nasal breathing in rhinitis.
In therapeutic concentrations it does not irritate nasal mucosa, does not cause hyperemia. Action occurs within a few minutes and lasts for 10-12 hours.
Indications
Acute respiratory diseases with rhinitis (runny nose), acute allergic rhinitis, pollinosis, sinusitis, eustachitis, otitis media (for reduction of nasopharyngeal mucosa edema).
Preparation of the patient for diagnostic manipulations in the nasal passages.
Contraindications
– Hypersensitivity to the drug components,
– arterial hypertension,
– tachycardia,
– pronounced atherosclerosis,
– glaucoma,
– atrophic rhinitis,
– hyperthyroidism,
– surgical interventions on the cerebral membranes (in the anamnesis),
– the condition after a transsphenoidal pituitaryectomy,
– children under 2 years of age – for the solution with a concentration of 0.05%,
– Children under 6 years of age – for the solution with a concentration of 0.1%,
– pregnancy.
Do not use during therapy with monoamine oxidase inhibitors (MAO) and tricyclic antidepressants, as well as with other drugs that increase blood pressure.
Dosage and administration
- Intranasally (into each nasal passage).
solution with 0.05% concentration: for children aged from 2 to 6 – 1-2 drops in each nostril 1-2 times a day; do not use more than 3 times a day. - Solution of the drug with 0.1% concentration: adults and children over 6 years of age – 2-3 drops in each nostril 2-3 times a day (if necessary, it may be repeated); the drug should not be used more than 3 times a day.
- The drug is used for not more than 7 days.
