Description
Sialor Pharmacodynamics
Preparation of silver (silver proteinate contains 7.5-8.5% silver). It has astringent, antiseptic and anti-inflammatory effect. It dissociates with the formation of silver ions that bind with the DNA of bacteria and prevent their reproduction on mucous membranes in conditions of local application. Mechanism of action of silver proteinate is based on the fact that silver ions precipitate proteins and form a protective film on the damaged mucous membrane, which helps to reduce the sensitivity of nerve endings and narrowing of blood vessels (which leads to reduction of edema), which in turn leads to inhibition of inflammatory reactions. Silver ions also inhibit the reproduction of various bacteria. It is active against Gram-positive and Gram-negative microorganisms: B. cereus, C. albicans, E. coli, P. aeruginosa, S. aureus, A. niger, S. abony and others.
Indications
Symptomatic therapy of acute nasopharyngitis, sinusitis; acute rhinitis (runny nose).
Contraindications
hypersensitivity to the drug, pregnancy, lactation, atrophic rhinitis, children under 3 years of age.
Usage during pregnancy and lactation
The drug is contraindicated during pregnancy and lactation; if it is necessary to use the drug, breast-feeding should be discontinued.
Directions for use and dosages
- Topically, as a 2% solution.
- Preparation of the solution to be carried out immediately before use.
- Ready to store the solution at room temperature. The solution should be used within 30 days after preparation.
- To prepare 2% solution, 1 tablet (200 mg) of the drug is dissolved in 10 ml of solvent (water for injection).
- How to prepare the drug solution before use:
1. Pour the solvent into the bottle
2. Add the tablet of Sialor to the bottle.
3. Shake until the tablet is dissolved (approx. 15 min.).
- Before using, it is recommended to rinse and clean the nasal passages.
- Children from 3 to 6 years of age – 1-2 drops in each nostril 3 times a day.
- Adults and children over 6 years – 2-3 drops in each nostril 3 times a day. The duration of treatment is 5-7 days.
- If after 7 days of treatment no improvement occurs or symptoms worsen or new symptoms appear, consult a doctor.
- Use the drug only according to those indications, that method of use and in those doses specified in the instructions.
