Description
Zinocap Pharmacodynamics
Zinc pyrithione has anti-inflammatory, antibacterial and antifungal activity. Antibacterial activity of zinc pyrithione is shown against a number of Gram-positive and Gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.).
Zinc pyrithione reduces intracellular ATP level, promotes depolarization of cell membranes, causing death of fungi and bacteria. Antifungal activity is especially pronounced when acting on Pityrosporum ovale and Pityrosporum orbiculare, which cause inflammation and excessive flaking in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action is not studied.
Indications
Psoriasis
Seborrheic dermatitis
Atopic dermatitis (eczema, neurodermatitis)
Contraindications
Hypersensitivity, children under 1 year of age.
Dosage and administration
- The drug is intended for external use.
- Used in adults and children from 1 year of age.
- Shake the bottle before use.
- Spray the drug on the affected skin area from a distance of 15 cm 2-3 times a day until clinical effect is achieved. For treating the scalp with the drug an additional nozzle is attached. It is recommended to continue using the drug for one week after symptoms disappear.
- Duration of treatment for:
- – psoriasis 1-1.5 months, repeated courses – when signs of exacerbation appear;
- – Seborrheic dermatitis 2 weeks;
- – Atopic dermatitis 3-4 weeks.
- If after treatment no improvement occurs or symptoms worsen or new symptoms appear, it is necessary to consult a doctor. Use the drug only according to the indications, the method of administration and in such doses as specified in the instructions for use.