Description
Iodoxid Pharmacodynamics
Antiseptic drug. It blocks amino groups of cellular proteins. It has a wide range of antimicrobial activity. It is active against bacteria (including E. coli, Staphylococcus aureus), fungi, viruses, protozoa.
The active ingredient of the drug – iodine – is in the form of a complex with polyvinylpyrrolidone (povidon), related to iodophores, which bind iodine. The concentration of active iodine is 0.1-1%. Upon contact with skin and mucous membranes iodine is gradually and evenly released, having a bactericidal effect on microorganisms. A thin colored layer remains at the place of application, which persists until all the iodine is released.
Indications
Acute and chronic inflammatory and infectious vaginal diseases (trichomonas, fungal, viral, nonspecific, mixed infections), bacterial vaginitis.
Prevention of infectious and inflammatory complications before gynecological interventions (induced termination of pregnancy, installation and removal of the IUD, cervical diathermic coagulation, hysterosalpingography, etc.).
Contraindications
Hypersensitivity to iodine and other components of the drug, thyrotoxicosis (hyperthyroidism), Duhring’s dermatitis herpetiformis, thyroid adenoma, concomitant use of radioiodine, children under 8 years of age.
Caution
Chronic renal failure, pregnancy, breast-feeding, advanced age.
Using during pregnancy and breast-feeding.
Iodine penetrates the placental barrier and is excreted with the breast milk. It is not recommended to use Iodoxid® from the second trimester of pregnancy and during breast-feeding. Application of the drug Yodoxid® during these periods is possible only if the expected benefits to mother overweigh the potential risk to fetus and child. If it is necessary to use the drug in these cases, the treatment is possible under individual medical supervision. In newborns and infants
children whose mothers used Iodoxid®, should monitor the thyroid function.
Dosage and administration
- Intravaginal. Pre-release the suppository from the outline cell packing, it is introduced, lying on the back, deep into the vagina. In acute vaginitis – 1 suppository 2 times a day for 7 days, in subacute and chronic vaginitis – 1 suppository 1 time a day before going to bed for 14 days (regardless of the phase of the menstrual cycle).
