Potassium aspartate, magnesium aspartate (Pananspar) 316 mg + 280 mg – [50 tablets]

The most important intracellular potassium (K+) and magnesium (Mg’+) cations play a key role in the functioning of numerous enzymes, in the formation of bonds between macromolecules and intracellular structures and in the mechanism of muscle contractility. The intra- and extracellular ratios of potassium, calcium, sodium, and magnesium ions influence myocardial contractility. Endogenous asparaginate acts as a conductor of ions: it has a high affinity for cells, due to the insignificant dissociation of its salts, ions in the form of complex compounds penetrate the cell. Magnesium asparaginate and potassium asparaginate improve myocardial metabolism. Magnesium / potassium deficiency predisposes to the development of arterial hypertension, coronary artery atherosclerosis, arrhythmias and metabolic changes in the myocardium.

For elimination of potassium and magnesium deficiency as part of combination therapy in various manifestations of coronary heart disease (including acute myocardial infarction); chronic heart failure;

Cardiac arrhythmias (including arrhythmias caused by overdose of cardiac glycosides)

Contraindications .

Hypersensitivity to any of the drug components, acute and chronic renal failure, hyperkalemia, hypermagnesemia, Addison’s disease, 1st – 3rd degree atrioventricular block, shock (including cardiogenic shock) (blood pressure < 90 mm Hg), amino acid metabolism disorders, severe myasthenia, hemolysis, acute metabolic acidosis, dehydration states, age less than 18 years (efficacy and safety have not been established).

Caution

Pregnancy (especially during the first trimester of pregnancy) and breast-feeding.

Usage during pregnancy and breast-feeding period

Use is possible if the potential benefit to the mother exceeds the possible risk to the fetus.

Potassium and magnesium asparaginate penetrate into the breast milk. If it is necessary to take the drug while breast feeding, breast feeding should be discontinued.