Description
Corvalol Pharmacodynamics
Combined drug, has a sedative and antispasmodic effect, facilitates the onset of natural sleep.
Ethylbromisovalerianat has sedative and antispasmodic effect caused by irritation, mainly of receptors in the mouth and nasopharynx, reduction of reflex excitability in the central nervous system and increased inhibition in the cortex and subcortical structures of the brain, as well as reducing the activity of central vasomotor centers and a direct local spasmolytic effect on smooth muscles.
Phenobarbital has a sedative (in small doses), hypnotic, muscle relaxant and antispasmodic effect, reduces the excitation of the central nervous system (CNS) and facilitates sleep, increases the sedative effect of other components.
Peppermint oil has a reflex vasodilatory, antispasmodic, mild choleretic, antiseptic. The mechanism of action is related to the ability to irritate the “cold” receptors of the mucous membrane of the mouth and expand reflexively mainly vessels of the heart and brain. It eliminates the phenomena of flatulence due to irritation of the mucous membrane receptors of the gastrointestinal tract (GIT), increasing intestinal peristalsis.
Indications
As a symptomatic (sedative and vasodilator) means for functional disorders of the cardiovascular system, the neurosis-like states, accompanied by increased irritability, problems falling asleep, tachycardia, states of agitation with marked autonomic manifestations, as antispasmodic agent – in spasms of the intestine.
Contraindications
– Hypersensitivity to the drug components;
-Severe renal and/or hepatic impairment;
– pregnancy;
– Breast-feeding period;
– children under 18 years of age (efficacy and safety have not been established);
– galactose intolerance, lactase deficiency.
Caution
Impaired liver and/or kidney function.
If you have one of the listed diseases/conditions, always consult your physician before taking the drug.
Administration during pregnancy and breast feeding
Using the drug Corvalol during pregnancy is contraindicated because the drug contains phenobarbital, which penetrates through the placenta and has teratogenic effect, has an adverse effect on the formation and further functioning of the central nervous system of the fetus and the newborn; it penetrates into the breast milk and may lead to physical dependence in the newborn. If it is necessary to use during breast-feeding, it is necessary to decide whether to stop breast-feeding.
Dosage and administration
- Taken orally, before a meal, with water.
- The dosage is set individually.
- Adults are usually prescribed 1-2 tablets 2 times a day. If tachycardia may increase the single dose of up to 3 tablets.
- The dosage of the drug shall be determined by the doctor individually.
