Description
Eluphor Pharmacodynamics
Nifuroxazide is an antimicrobial agent, a nitrofuran derivative.
Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp.
Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.
Resistant to Nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.
Supposedly blocks dehydrogenase activity and inhibits respiratory chains, tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell.
Does not disturb the balance of intestinal microflora
In acute bacterial diarrhea restores intestinal eubiosis.
In case of infection with enterotropic viruses prevents the development of bacterial superinfection.
Indications
Acute bacterial diarrhea without worsening of the general state, fever and intoxication
Contraindications
– Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug;
– fructose intolerance;
– glucose-galactose malabsorption syndrome or insufficiency of sucrose and isomaltase;
– pregnancy;
– period of newborn infancy (less than 1 month), prematurity.
Use in pregnancy and during breastfeeding:
No teratogenic effects have been observed in animal studies. However, as a precautionary measure, it is not recommended to take nifuroxazide during pregnancy.
During the lactation period, it is possible to continue breastfeeding in case of a short course of treatment with the drug. It is necessary to consult a doctor.
Directions for use and dosages
- Used orally.
- A dosage spoon of 5 ml with a graduation mark of 2.5 ml is used for dosing.
- Shake the suspension well before use.
- Children from 1 to 6 months: 100 mg (2.5 ml) 2-3 times a day (interval between doses 8-12 hours).
- Children from 6 months to 3 years of age: 100 mg (2.5 ml) 3 times a day (interval between doses is 8 hours).
- Children from 3 to 6 years of age: 200 mg (5 ml) 3 times a day (interval between doses is 8 hours).
- Children 6 to 18 years of age: 200 mg (5 ml) 3 to 4 times a day (the interval between doses is 6 to 8 hours).
- Adults: 200 mg (5 ml) 4 times a day (interval between doses is 6 hours).
- The course of treatment is 5-7 days, but no more than 7 days.
- If during the first 3 days of treatment there is no improvement, you should consult a doctor.
- Use the drug only in accordance with the method of use and in those doses that are listed in the instructions.
- If necessary, please consult a physician before using the drug.