Description
Nifuroxazide (Elufor) capsules Pharmacodynamics
Nifuroxazide is a nitrofuran derivative with antimicrobial action.
Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolyticus, Staphylococcus spp.
Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.
Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.
Supposedly blocks dehydrogenase activity and inhibits respiratory chains, tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. It does not disturb the equilibrium of the intestinal microflora. In acute bacterial diarrhea restores intestinal eubiosis. In case of infection with enterotropic viruses prevents the development of bacterial superinfection.
Indications
Acute bacterial diarrhea without worsening of the general condition, fever and intoxication.
Contraindications
– Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug;
– Children under 3 years of age (for this dosage form);
– pregnancy;
– sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.
USE IN PREGNANCY AND DURING BREASTFEEDING
No teratogenic effect has been shown in animal studies. However, as a precautionary measure, taking nifuroxazide during pregnancy is not recommended
During the lactation period, it is possible to continue breastfeeding in case of a short course of treatment with the drug. It is necessary to consult a doctor.
Dosage and administration method
- Inside. The capsule should be swallowed whole with a small amount of water. Adults: 1 capsule 200 mg 4 times a day (interval between doses of 6 hours).
- Children 6 to 18 years of age: 1 capsule 200 mg 3-4 times a day (interval between doses of 6-8 hours).
- Children from 3 to 6 years: 1 capsule 200 mg 3 times a day (interval between doses of 8 hours).
- Course of treatment for 5-7 days, but no more than 7 days.
- If during the first 3 days of treatment no improvement has occurred, you should consult a doctor
- Use Nifuroxazide (Elufor) capsules only in accordance with the method of use and in those doses that are listed in the instructions. If necessary, please consult a physician before using the drug.