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Naftifine (Mycoderil) cream 1% – [30 g tube]


Antifungal drug for external use

SKU: 62094 Category:


Mycoderil Pharmacodynamics
Naftifin is an antifungal agent for external use, belonging to the class of allilamines. The mechanism of action is related to the inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosgerol, which is part of the cell wall of the fungus. It is active against dermatophytes such as Trichophyton, Epidermophyton and Microsporum, molds (Aspergillus spp.), yeasts (Candida spp., Pityrosporum) and other fungi (such as Sporothrix schenckii). Against dermatophytes and aspergillus naphthifin acts fungicidal. Against yeast fungi the drug exhibits fungicidal or fungistatic activity depending on the strain of the microorganism. It has antibacterial activity against Gram-positive and Gram-negative microorganisms that can cause secondary bacterial infections. It has anti-inflammatory activity, which contributes to the rapid disappearance of inflammatory symptoms, especially itching.

– Fungal infections of smooth skin and skin folds (tinea corporis, tinea inquinalis);
– Interfinger mycoses (tinea manum, tinea pedum);
– Fungal infections of the nails (onychomycoses);
– skin candidiasis;
– pityriasis;
– Dermatomycoses (with or without itching)

Hypersensitivity to naphthifine, benzyl alcohol or other drug components; pregnancy and lactation (safety and efficacy of the drug in this group of patients has not been studied).
Childhood (experience with clinical use is limited).
Pregnancy and lactation:
Use of the drug in pregnancy and during lactation is contraindicated (safety and efficacy of the drug in this category of patients has not been studied).

Directions for use and dosages.

  • Outwardly.
  • Micoderil® is applied once daily to the affected skin surface and adjacent areas after thorough cleaning and drying (leaving approximately 1 cm of healthy skin at the edge of affected area).
  • Duration of therapy in dermatomycosis – 2-4 weeks (if necessary – up to 8 weeks), in candidiasis – 4 weeks.
  • In case of nail affection Mikoderil® is applied 2 times a day to the affected nail. Before the first use of the drug, remove the affected part of the nail with scissors or a nail file as much as possible.
  • The duration of therapy for onychomycosis is up to 6 months.
  • To prevent relapse, treatment should be continued for at least 2 weeks after the disappearance of clinical symptoms.