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Loratadine-Eko syrup 5 mg/5 ml – [100 ml vial]

$12.42

Histamine h1 receptor blocker. Antiallergic drug

SKU: 61913 Category:

Description

Loratadine-ECOlab Pharmacodynamics
Loratadine is the active substance of the drug Loratadine-ECOlab is a tricyclic compound with a marked antihistamine action and is a selective blocker of peripheral H1-histamine receptors. It has a rapid and prolonged antiallergic effect. Onset of action is within 30 minutes after taking the medicine, the antihistamine effect reaches its peak 8-12 hours after ingestion and lasts up to 24 hours.
Loratadine does not penetrate through the blood-brain barrier and has no effect on the central nervous system. It has no clinically significant anticholinergic or sedative effect, i.e. it does not cause drowsiness and does not affect the speed of psychomotor reactions when used in the recommended doses. Administration of the drug Loratadine-ECO does not lead to prolongation of the QT interval on electrocardiography (ECG).
During long-term treatment, no clinically significant changes in vital signs, physical examination data, results of laboratory tests or electrocardiography were observed.
Loratadine has no significant selectivity for H2-histamine receptors. It does not inhibit norepinephrine reuptake and has practically no effect on cardiovascular system or rhythm driver function.

Indications
Seasonal (pollinosis) and year-round allergic rhinitis and allergic conjunctivitis – elimination of the symptoms associated with these diseases: sneezing, nasal mucosa itching, rhinorrhea, itching and burning sensations in the eyes, lacrimation.
Chronic idiopathic urticaria.

Contraindications
Hypersensitivity to loratadine or any other component of the drug.
Childhood under 2 years of age.
Breast-feeding period.
Patients with fructose intolerance – due to the presence of sorbitol, which is part of the syrup.

Dosage and administration

  • Inside, regardless of the time of the meal.
  • It is recommended to adults, including elderly people and teenagers above 12 years old to take the preparation Loratadine-ECOLab in dose of 10 mg (10 ml of syrup) once a day.
  • When using the drug in elderly patients and in patients with the presence of chronic renal failure, no dose adjustment is required.
  • For children aged 2 to 12 years it is recommended to prescribe the dose of Loratadine-ECOLab depending on body weight:
    – if the body weight is 30 kg or less – 5 mg (5ml) of syrup once a day;
    – for body weight over 30 kg – 10 mg (10 ml) syrup 1 time per day.
  • For adults and children with severe liver dysfunction the initial dose should be: if body weight 30 kg or less – 5 mg (5 ml) syrup every other day, if body weight over 30 kg – 10 mg (10 ml) syrup every other day.