Description
Methyluracil Pharmacodynamics
Immunostimulant, dioxomethyltetrahydropyrimidine. It promotes normalization of nucleic acid metabolism, accelerates processes of cell regeneration in wounds, accelerates growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of gastrointestinal mucosa), stimulates erythro- and leukopoiesis, cellular and humoral factors of immunity. It has anabolic activity and anti-inflammatory effect. When used externally it also has a photoprotective effect.
Indications
For topical use: proctitis, sigmoiditis, ulcerative colitis.
Contraindications .
Hypersensitivity to methyluracil.
For oral use: leukemia (leukemic forms, especially myeloid), lymphogranulematosis, hemoblastosis, malignant bone marrow diseases.
For external and local use: excessive granulation in the wound.
Directions for use and dosages
- Rectally is used in adults by 0.5-1 g 3-4 times; in children aged 3-8 years – by 250 mg/, in children aged 8-15 years – by 500 mg/ The course of treatment is from 1 week to 4 months.
