Description
Methyluracil Pharmacodynamics
Immunostimulant, dioxomethyltetrahydropyrimidine. It promotes normalization of nucleic acid metabolism, accelerates processes of cell regeneration in wounds, accelerates growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of gastrointestinal mucosa), stimulates erythro- and leukopoiesis, cellular and humoral factors of immunity. It has anabolic activity and anti-inflammatory effect. When used externally it also has a photoprotective effect.
Indications
For external use: sluggish wounds, burns, bone fractures, photodermatitis, trophic ulcers, bedsores, deep wounds.
Contraindications
Hypersensitivity to methyluracil.
Oral use: leukemia (leukemic forms, especially myeloid), lymphogranulematosis, hematoblastosis, malignant bone marrow diseases.
For external and local use: excessive granulation in the wound
Dosage and administration
- When applied topically the dosing regimen is set individually, depending on the dosage form used. The frequency of dressing changes depends on the depth and area of the wound surface, the intensity of exudation and the presence of necrotic masses.