Diclofenac gel 5% – [30 g tube]

Description

Diclofenac Pharmacodynamics
The active ingredient – diclofenac – is a non-steroidal anti-inflammatory drug with pronounced analgesic, anti-inflammatory and antipyretic properties. By indiscriminately inhibiting cyclooxygenase type 1 and 2, it disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.
In rheumatic diseases it reduces swelling, hyperemia and pain at rest and while moving, morning stiffness and joint swelling, improving their functional ability. In post-operative and traumatic injuries it quickly suppresses pain and inflammation in the area of application of the drug, promotes resorption of post-traumatic hematoma.

Indications
– Back pain in inflammatory and degenerative diseases of the spine (radiculitis, osteoarthritis, lumbago, sciatica),
– Pain in the joints (finger joints, knee joints, etc.) in osteoarthritis,
– Pain in the muscles (due to sprains, strains, bruises, injuries),
– Inflammation and swelling of soft tissues and joints due to injuries and rheumatic diseases (tendovaginitis, bursitis, periarticular tissues).
It is intended for symptomatic therapy, reduction of pain and inflammation at the time of use, does not affect the progression of the disease.

Contraindications
Hypersensitivity to diclofenac and other components of prepcrates.
Complete or incomplete combination of bronchial asthma, angioedema or urticaria, recurrent polyposis of the nose and sinuses and intolerance to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (including a history).
Pregnancy (III trimester), breastfeeding, children (under 12 years). Violation of the integrity of the skin in the intended place of application.
Caution: hepatic porphyria (exacerbation), gastrointestinal erosive-ulcerative lesions in the history (including gastric and duodenal ulcers), severe liver and renal function disorders, chronic heart failure, blood clotting disorders (including hemophilia and hemophilia). including hemophilia, prolongation of bleeding time, susceptibility to bleeding), bronchial asthma, advanced age, pregnancy (I and II trimester) If you have any of the above mentioned diseases, consult a physician before using the drug.
Use during pregnancy and breastfeeding
Because of the lack of data on using diclofenac during pregnancy, it is recommended to use the drug during I and II trimester of pregnancy only by prescription, comparing the benefits for mother and risks for fetus.
The drug is contraindicated in the third trimester of pregnancy due to the possibility of decreased uterine tone, impaired renal function of the fetus with subsequent development of oligo and/or premature closure of the fetal arterial duct.
Due to the lack of data on the penetration of diclofenac into the breast milk, it is recommended to use the drug during breast-feeding only by prescription, comparing the benefit to the mother and the risk to the fetus. If use of the drug is still necessary, it should not be applied to the mammary glands or to a large area of skin and should not be used for a long period of time.
There are no data on the use of diclofenac and its effect on fertility in humans.

How to use and dosages

• Outwardly.
• Adults and children over 12 years of age apply the drug to the skin 2-3 times a day, in a dose of 2 g (about 4 cm with a fully open tube). Apply a thin layer to the skin over the inflammation and gently rub it in.
• Single dose of the drug – 2 g.
• The maximum daily dose of the gel should not exceed 6 g.
• If after 7 days of use the therapeutic effect is not observed or the condition worsens, you should consult a doctor. The course of treatment is not more than 14 days for post-traumatic inflammations and rheumatic diseases of soft tissues. The need for a longer application of the drug is determined by the doctor.
• If the hands are not the area of localization of pain, they should be washed after applying the gel.
• Apply in minimally effective doses in a minimally short course.