Description
Polysorb MF Pharmacodynamics
Polisorb MF is an inorganic non-selective polyfunctional enterosorbent based on highly dispersed silica with a particle size of up to 0.09 mm and the chemical formula SiO2. Polysorb MF has sorption, detoxifying, antioxidant and membrane stabilizing properties.
The preparation adsorbs from intestinal contents and removes from the body exogenous and endogenous toxins of different origin including pathogenic bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metal salts, radionuclides and alcohol.
Polysorb MF also adsorbs some products of the body’s metabolism (including bilirubin, urea, cholesterol and lipid complexes).
Indications
– Acute and chronic intoxications in children and adults of different etiologies;
– Acute intestinal infections (including food toxic infections);
– diarrheal syndrome of non-infectious etiology;
– intestinal dysbacteriosis (as part of combination therapy);
– purulent-septic conditions;
– Acute poisoning by potent and poisonous substances (including drugs, ethanol, alkaloids, salts of heavy metals);
– Food and drug allergies;
– hyperbilirubinemia (including viral hepatitis);
– Hyperazotemia (including chronic renal failure);
– Living in environmentally disadvantaged regions and work in harmful industries (in order to prevent).
Contraindications
– Gastric and duodenal ulcer in the acute phase;
– gastrointestinal bleeding;
– intestinal atony;
– Individual intolerance to the drug.
Dosage and administration
- Adults administer Polisorb MF in an average daily dose of 100-200 mg/kg body weight (6-12 g). Frequency of administration – 3-4 Maximum daily dose in adults is 330 mg/kg body weight (20 g).
- Daily dose of Polisorb MF for children depends on body weight.
- Patient’s body weight (kg) Daily dose (g)
- minimum average maximum
- 10.0 1.0 1.5 2.0
- 15.0 1.5 2.25 3.0
- 20.0 2.0 3.0 4.0
- 25.0 2.5 3.75 5.0
- 30.0 3.0 4.5 6.0
- 40.0 4.0 6.0 8.0
- 50.0 5.0 7.5 10.0
- 60.0 6.0 9.0 12.0
- 1 teaspoon of Polisorb MF “topped” contains 1 g of the drug, 1 tablespoon “topped” – 3 g.
- The drug is taken orally only in the form of water suspension. For making the suspension, the required amount of the drug Polisorb MF is thoroughly mixed in 1/4-1/2 cup water.
- The drug is taken 1 hour before a meal or taking other drugs. Before each meal, it is recommended to prepare a fresh suspension.
- In food allergies should take the drug immediately before or during meals.
- The duration of treatment depends on the diagnosis and severity of the disease. The course of treatment for acute intoxication is 3-5 days, with allergic diseases and chronic intoxications – up to 10-14 days. After 2-3 weeks it is possible to repeat the course of treatment.
