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Clotrimazole-Akrikhin vaginal 100 mg – [6 tablets]


Drug with antifungal action for local use in gynecology

SKU: 61761 Category:


Clotrimazole-Acrihin Pharmacodynamics
Clotrimazole-Acrihin is an antifungal agent of broad spectrum for topical use. Antimycotic effect of the active active substance clotrimazole (imidazole derivative) is associated with disruption of ergosterol synthesis, which is part of the cell membrane of fungi, which changes membrane permeability and causes subsequent cell lysis. In low concentrations it is fungistatic and in high concentrations it is fungicidal, and not only on proliferating cells. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in hydrogen peroxide concentration to toxic levels, which also helps destroy fungal cells.
Effective against dermatophytes, yeast-like and mold fungi as well as Pityriasis versicolor (Malazessia furfur) and erythrazma pathogen. It has antimicrobial action against Gram-positive (staphylococci, streptococci) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

– Genital infections caused by yeast-like fungi of the genus Candida and/or Trichomonas vaginalis (candidiasis vulvovaginitis, trichomoniasis);
– genital superinfections caused by clotrimazole-sensitive microorganisms;
– Sanitation of the birth canal before delivery.

Hypersensitivity to clotrimazole or excipients, in the first trimester of pregnancy. The use of tablets during menstruation should be avoided.
With caution:
Period of lactation.
Use in pregnancy and during breast-feeding:
Clinical and experimental studies have not found that the use of the drug during pregnancy or during breast-feeding has adverse effects on the health of the woman or the fetus (child). However, the question on the appropriateness of the drug administration should be solved individually after consultation with the physician.

Dosage and administration

  • Topically.
  • Intravaginal use only. The vaginal tablets are introduced in the evening into the vagina as deeply as possible in a supine position with slightly bent legs, 1 vaginal tablet (100 mg) daily for 6 days. A second course of treatment is possible after a doctor’s consultation.
  • A single administration of one tablet is recommended for sanation of the birth canal.