Home  /   Products  /   Cardiovascular  /   Cinnarizin 25 mg – [50 tablets]

Cinnarizin 25 mg – [50 tablets]

$12.42

Slow calcium channel blocker

SKU: 63321 Category:

Description

Cinnarizine Pharmacodynamics
Selective slow calcium channel blocker, decreases influx of calcium ions into cells and decreases their content in plasma membrane depot, decreases tone of arteriolar smooth muscle, increases vasodilatory action of carbon dioxide. By directly affecting vascular smooth muscle, it reduces their response to biogenic substances (adrenaline, noradrenaline, dopamine, angiotensin, vasopressin). It has a vasodilator effect (especially on brain vessels), without a significant effect on blood pressure. It has moderate antihistamine activity, reduces the excitability of the vestibular apparatus, reduces the tone of the sympathetic nervous system. Effective both at initial and at chronic insufficiency of cerebral circulation (including patients in the residual stage of ischemic stroke). In patients with peripheral circulatory disorders improves blood supply to organs and tissues (including myocardium). Increases the elasticity of red blood cell membranes, their ability to deform, reduces blood viscosity. Increases muscle resistance to hypoxia.

 

Indications
Ischemic stroke, post-stroke conditions (including post-hemorrhagic stroke), conditions after craniocerebral injuries, discirculatory encephalopathy, vestibular disorders (including Meniere’s disease; vertigo, tinnitus, nystagmus, nausea and vomiting of labyrinthine origin), prevention of kinetosis (“road sickness” – sea and air sickness), migraine (prevention of attacks), senile dementia; Peripheral circulatory disorders (“intermittent” claudication, obliterating atherosclerosis, obliterating thrombangiitis (Buerger’s disease), Raynaud’s disease, diabetic angiopathy, thrombophlebitis, trophic disorders (including trophic and varicose veins), and other disorders of the peripheral nervous system. including trophic and varicose ulcers, pre-gangrenous conditions).

 

Contraindications .
Hypersensitivity, pregnancy, lactation.
With caution:
With caution in Parkinson’s disease.

 

Dosage and administration
  • Inside, preferably after a meal. In violation of cerebral circulation – 25-50 mg (1 -2 tablets) three times a day; in violation of peripheral circulation – 50-75 mg (2-3 tablets) three times a day; in vestibular disorders – 25 mg three times a day; in kinetosis (“road” disease): adults – 25 mg half an hour before driving (repeated 25 mg in 6 hours if necessary).
  • The dose for children is ½ of the dose recommended for adults.
  • If there is high sensitivity to Cinnarizine, treatment begins with ½ dose, increasing it gradually. The course of treatment is from several weeks to several months.