Description
Chondrogard Pharmacodynamics
A high-molecular-weight mucopolysaccharide that affects metabolic processes in hyaline cartilage.
It reduces degenerative changes in cartilage of joints, accelerates its repair processes, stimulates the synthesis of proteoglycans.
Treatment with the drug reduces pain and improves mobility of affected joints. In the treatment of degenerative joint changes with the development of secondary synovitis, a positive effect can be observed 2-3 weeks after the start of drug administration: joint pain decreases, clinical manifestations of reactive synovitis disappear, the volume of movements in affected joints increases. The therapeutic effect persists for a long time after the end of treatment.
Indications
– Degenerative-dystrophic diseases of the joints and spine:
– osteoarthritis of the peripheral joints;
– Intervertebral osteochondrosis and osteoarthritis.
– To accelerate the formation of the bone callus on fractures.
Contraindications
– Hypersensitivity to Chondrogard or its components;
– Bleeding and a tendency to bleeding;
– thrombophlebitis;
– in case of intraarticular injection: active inflammatory or infectious processes in the joint, active skin disease or skin infection in the area of the intended injection;
– children;
– Pregnancy and lactation (data on the safety of using the drug are not available at the moment).
Dosage and administration method
- Chondrogard is administered intramuscularly – 100 mg every other day. If tolerated well, the dose is increased to 200 mg, starting with the fourth injection.
- The course of treatment is 25-30 injections. If necessary, a second course of treatment may be carried out after 6 months.
- In osteoarthritis of large joints it is possible to combine intraarticular and intramuscular injection methods.
- Up to 5 intraarticular injections of 200 mg with 3 days interval between injections and 16 intramuscular injections of 200 mg with 1 day interval between injections (every other day).
- Intra-articular injection of the drug is carried out under aseptic conditions by a specialist trained in the technique of intra-articular injection.
- Depending on the size of the joint, up to 2 ml of Chondrogard can be injected into the joint cavity.
- After intra-articular injection of the drug the puncture site is lubricated with an alcohol napkin and a bactericidal plaster is applied.
- For bone callus formation the treatment course is 3-4 weeks (10-14 injections intramuscularly every other day).