Description
Cereton Pharmacodynamics
Nootropic. A central cholinostimulant containing 40.5% metabolically protected choline. Metabolically protected promotes the release of choline in the brain. Provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in central nervous system, activates reticular formation. It increases linear velocity of blood flow on the side of traumatic brain injury, normalizes spatial and temporal characteristics of spontaneous bioelectrical activity of the brain, regresses focal neurological symptoms and restores consciousness, has a positive effect on the cognitive and behavioral responses of patients with cerebral vascular disease (discirculatory encephalopathy and residual effects of circulatory disorders of the brain). It has a preventive and corrective effect on pathogenetic factors of involutional psychoorganic syndrome, changes phospholipid composition of neuronal membranes and reduces cholinergic activity. Stimulates dose-dependent release of acetylcholine under physiological conditions; participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, neuronal membrane plasticity, receptor function. It has no effect on the reproductive cycle and has no teratogenic, mutagenic effect.
Indications
– Acute and recovery periods of severe craniocerebral trauma and ischemic stroke, the recovery period of hemorrhagic stroke, proceeding with focal hemispheric symptoms or symptoms of brain stem damage;
– psycho-organic syndrome against a background of degenerative and involutionary changes of the brain;
– cognitive disorders (disorders of thought function, memory, confusion, consciousness, disorientation, decreased motivation, initiative and ability to concentrate), including in dementia and encephalopathy;
– senile pseudomelancholia.
Contraindications
– Hypersensitivity to Cereton injections or its components;
– Hemorrhagic stroke (acute stage);
– Childhood under 18 years of age;
– pregnancy;
– Breast-feeding period.
Pregnancy and lactation:
The use of the drug Cereton injections during pregnancy and during breast-feeding is contraindicated. Breast-feeding should be stopped during therapy with Cereton.
Dosage and administration method
Solution for intravenous and intramuscular administration. In acute conditions, Cereton injections are administered intravenously (slowly) or deeply intramuscularly (slowly) at 1000 mg / day (1 amp.) for 10-15 days.