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Description
Cereton Pharmacodynamics
Cereton 400 mg is Choline alfoscerate, which is a cholinomimetic of central action with predominant effect on the central nervous system.
The drug contains 40.5% of choline that is released from the compound in the brain; choline is involved in the biosynthesis of acetylcholine (one of the main mediators of nerve excitation). Alphoscerate is biotransformed to glycerophosphate, which is a precursor of phospholipids.
Acetylcholine has a positive effect on nerve impulse transmission, and glycerophosphate participates in the synthesis of phosphatidylcholine (membrane phospholipid), as a result membrane elasticity and receptor function are improved.
Cereton’8 enhances metabolic processes and activates the structures of the reticular formation of the brain.
It has a preventive and corrective effect on factors of involutional psychoorganic syndrome, such as changes in phospholipid composition of neuronal membranes and decreased cholinergic activity.
Pharmacodynamic studies have shown that Cereton acts on synaptic, including cholinergic transmission of nerve impulse (neurotransmission), neuronal membrane plasticity and receptor function.
Indications
– Impaired cerebral circulation of the ischemic type (acute and recovery periods) and hemorrhagic type (recovery period).
– Psycho-organic syndrome against involutional and degenerative processes of the brain.
– Consequences of cerebrovascular insufficiency or primary and secondary cognitive disorders in the elderly, characterized by memory impairment, confusion, disorientation, decreased motivation and initiative, reduced concentration of attention.
– Behavioral and affective disorders in old age: emotional lability, increased irritability, decreased interest; senile pseudomelancholy.
– Multi-infarct dementia.
Contraindications
-Hypersensitivity to Cereton 400 mg.
– Pregnancy.
-Period of breast-feeding.
-Children under 18 years of age (due to lack of data).
Usage during pregnancy and lactation
Administration of the drug Cereton during pregnancy and breast-feeding is contraindicated.
Dosage and administration
- Cereton 400 mg capsules are taken orally before a meal with water.
- One capsule (400 mg) 2-3 times a day. The duration of treatment the doctor determines individually, depending on the clinical state and characteristics of the disease, age and tolerance to Cereton 400 mg.
