Bifidumbacterin for vaginal or rectal administration – [10 suppositories]

Description

Bifidumbacterin suppositories Pharmacodynamics
Bifidumbacterin is a microbial mass of live bifidobacteria strain Bifidobacterium bifidum № 1, lyophilically dried in a culture medium with the addition of protective (sucrose-gelatin) drying medium and lactose (monohydrate), molded into suppositories.
Live microbial cells of bifidobacteria have high antagonistic activity against pathogenic and opportunistic microbes, including staphylococci, Proteus, enteropathogenic Escherichia coli, shigella, yeast-like fungi, which determines the normalizing effect of the drug in disorders of intestinal and vaginal biocenosis. Displacement of pathogenic and conditionally pathogenic microflora helps to restore normoflora.

Indications
Bifidumbakterin suppositories are used rectally for the treatment of adults and children over 3 years.
Rectally in adults and children:
– Chronic colitis of various etiologies with pronounced pathological processes in the distal parts of the intestine;
– Medical treatment of patients who had acute intestinal infections in the presence of intestinal dysfunction, excretion of pathogens or pronounced dysbacteriosis of various etiologies;
Vaginally in adults:
– Nonspecific colpitis (not associated with gonococcal, trichomonad and other specific infections); administered as an independent agent or after completion of antibacterial therapy;
– vaginal dysbiosis, including bacterial vaginosis (gardnerellosis); prescribed as an independent agent or in combination with immunobiological drugs;
– Subacute and chronic stages of vaginal inflammatory processes, prescribed after the completion of antibiotic therapy to normalize the microflora;
– hormone-dependent colpitis: senile, etc.; prescribed as an independent agent against the background of specific hormonal therapy;
– Preparation for routine gynecological surgery in order to prevent postoperative infectious complications;
– Prenatal preparation of pregnant women “at risk” for the development of inflammatory diseases in order to prevent and treat vaginal dysbiosis;
– as an adjunct in the treatment of urogenital infections and other sexually transmitted diseases: gonorrhea, urogenital chlamydia, genital herpes, etc. The drug is used to restore normal microflora in combination with or after specific antimicrobial, antiviral and immunomodulatory therapy.
Perhaps a combined use of suppositories and oral forms of Bifidobacterium bifidum on the advice of a physician.

Contraindications
Hypersensitivity to the components of the drug.
The drug is used rectally in children from 3 years old.
The drug is used vaginally in adults.
Precautions for use:
Before starting treatment, it is necessary to consult a doctor.
Use during pregnancy and lactation:
Bifidobacteria are representatives of normal human microflora. Preparations made on their basis can be used during pregnancy and lactation (see Indications for use).

Dosage and administration

• Bifidumbakterin administered rectally to adults and children from 3 years old, vaginally – adults.
  – In intestinal diseases suppositories are used rectally 3 times a day for 1 to 2 suppositories at a time in combination with oral doses of Bifidobacterium bifidum according to the instructions for use of a particular drug. The duration of treatment after an acute intestinal infection is 7-10 days, with prolonged and chronic forms of the disease, intestinal dysbacteriosis 15-30 days or more.
  – In gynecological practice: non-specific colpitis, vaginal dysbiosis, senile vaginitis hormonal nature, etc. Bifidumbacterin is used vaginally by 1 suppository 2 times a day for 5-10 days.
  – During the prenatal preparation of pregnant women of the “risk group” if the vaginal discharge is not clear to degree III-IV, Bifidumbacterin is used vaginally for 1 suppository 1-2 times a day for 5-10 days or more with monitoring of the recovery of vaginal discharge clear to degree I-II and the disappearance of clinical symptoms.
  – In order to prevent purulent-septic complications during elective gynecological operations, Bifidumbacterin is used vaginally for 1 suppository 1-2 times a day for 5-10 days before the anticipated operation.
  – Reconstitution therapy after administration of antibiotics: Bifidumbacterin is used rectally or vaginally, according to the prescription of the doctor, 1 suppository 1-2 times a day for 10 days. If necessary, the course may be repeated after 3-4 months.
  – When used against the background of treatment with antibacterial, antiviral and immunomodulatory drugs, Bifidumbacterin is used rectally or vaginally, as prescribed by the doctor, 1 suppository 1-2 times daily for 5-10 days.
• If after the course of treatment no improvement occurs or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor.
• Use Bifidumbacterin only according to those indications, that method of use and in those doses specified in the instructions.