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Aminodihydrophtalazinedione sodium (Galavit) rectal 100 mg – [10 suppositories]

$57.96

Immunomodulatory and anti-inflammatory drug

SKU: 61318 Category:

Description

Galavit Pharmacodynamics
The mechanism of action of the drug is associated with its ability to regulate
functional and metabolic activity of innate and adaptive immunity cells (monocytes, macrophages, neutrophils, natural killers, etc.). Galavit normalizes phagocytic activity of monocytes/ macrophages, bactericidal activity of neutrophils and cytotoxic activity of NK-cells.
At the same time, restoring the reduced activity of innate and adaptive immunity cells, the drug increases the body’s resistance to infectious diseases.
Moreover Galavit normalizes antibody formation, increases functional activity (affinity) of antibodies.
At inflammatory diseases the preparation reversibly for 6-8 hours inhibits excessive synthesis by overactivated macrophages of tumor necrosis factor-α, interleukin-1, interleukin-6 and other pro-inflammatory cytokines which level determines the degree of inflammatory reactions, their
cyclicity, as well as the severity of intoxication of the body. Galavit decreases the production of hyperactivated macrophages of reactive oxygen species, thus
thereby reducing the level of oxidative stress and protecting tissues and organs from the damaging effects of radicals.
Normalization of excessively high functional activity of phagocytic cells leads to restoration of their antigen-presenting and regulatory functions, reducing the level of autoaggression.
The drug has no allergizing, mutagenic, embryotoxic, teratogenic and carcinogenic effects.

Indications
As an immunomodulatory and anti-inflammatory agent in the treatment of immunodeficiency disorders in adults and adolescents over 12 years:
– Infectious-inflammatory urogenital diseases (urethritis of chlamydial and trichomonad etiology; chlamydial prostatitis, acute and chronic salpingo-oophoritis, endometritis);
– Purulent inflammatory diseases of the pelvic organs;
– Chronic recurrent diseases caused by the herpes virus;
– Diseases caused by the papilloma virus;
– Postoperative rehabilitation of patients with uterine myoma;
– Complications of postoperative period in women of reproductive age;
– Postoperative pyo-septic complications and their prevention (including cancer patients);
– Chronic recurrent furunculosis, rye;
– nonspecific prevention and treatment of influenza and acute respiratory infections;
– inflammatory diseases of the mucous membranes of the mouth and throat, periodontal disease;
– viral hepatitis;
– Infectious intestinal diseases accompanied by intoxication and/or diarrhea
– Peptic ulcer and duodenal ulcer
– Asthenic conditions, neurotic and somatoform disorders, reduced physical performance (including athletes); mental
Behavioral and postabstinence disorders with alcohol and drug dependence

Contraindications
Hypersensitivity to Galavit and other components of the drug, pregnancy and breastfeeding, children under 12 years of age.
Use during pregnancy and breast-feeding period:
Use of the drug is contraindicated in pregnancy and during breast-feeding.

Dosage and administration

  • Rectally. The suppository is freed from the contoured package and then inserted into the rectum. It is recommended to free the intestines beforehand.
  • The dose and duration of application of the drug depends on the nature, severity and duration of the disease.
    – In urogenital diseases
    – Urethritis of chlamydial and trichomonadic aetiology, chlamydial prostatitis: 1 day 1 suppository twice and then 1 every other day. The course of 10-15 suppositories (depending on the severity of the pathological process).
    – In salpingo-oophoritis, endometritis in the acute period: 2 days of 2 suppositories once a day, then one suppository at an interval of 72 hours. In the chronic period: 5 days with 1 suppository once a day, then one suppository every 72 hours. The course is 20 suppositories.
    – In acute and chronic
  • Pelvic purulent diseases – in the acute period: 1 day 2 suppositories once, 3 days one suppository daily, then one every other day for 5 days. The course of 10 suppositories. In the chronic period: 5 days 1 suppository once daily, then one every 72 hours. The course of 20 suppositories.
    – In chronic recurrent diseases caused by the herpes virus: 1 suppository daily 5 suppositories, then 1 suppository every other day – 15 suppositories.
    – In diseases caused by the papilloma virus: 5 days 1 suppository 1 time a day, then 1 suppository every other day. The course of 20 suppositories.
    – For postoperative rehabilitation of patients with uterine myoma and complications of the postoperative period in women of reproductive age:
    5 days 1 suppository once a day, then one suppository every other day. The course is 15 suppositories.
    – For prevention and treatment of surgical complications in pre- and postoperative period (including cancer patients): Prescribed 1 suppository 1 time per day. 5 suppositories before surgery, 5 suppositories after surgery, one every other day and 5 suppositories – at intervals of 72 hours. If the course of the disease is severe, the initial dose is 2 suppositories once or twice a day with one suppository. The course is 20 suppositories.
    – In chronic recurrent furunculosis, rust: 5 days with one suppository once a day, then one suppository every other day. The course of 20 suppositories.
    – For non-specific prevention and treatment of influenza and acute respiratory infections: one suppository 1 time a day. The course of 5 days.
    – In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal disease: The initial dose of 1 suppository daily – 5 suppositories, then one suppository at intervals of 72 hours. The course of 15 suppositories.
    – In viral hepatitis: the initial dose is 2 suppositories once, then one suppository twice a day until relief of symptoms of intoxication and inflammation. Subsequent continuation of the course of 1 suppository at intervals of 72 hours. The course of 20 -25 suppositories.
    – In acute infectious intestinal diseases accompanied by diarrheal syndrome: the initial dose is 2 suppositories once, then 1 suppository 2 times a day until relief of symptoms of intoxication. Further continuation of the course of 1 suppository at intervals of 72 hours is possible. The course of 20-25 suppositories.
    – With gastric and 12 duodenal ulcers in the acute period: 2 days 2 suppositories 1 time a day, then 1 suppository at an interval of 72 hours. The course of 15-25
    suppositories. In the chronic period: 5 days, 1 suppository 1 time a day, then 1 suppository 72 hours apart. The course of 20 suppositories. – In asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and postabstinence disorders, in patients with alcohol and drug dependence: 5 days with one suppository daily, then one suppository every 72 hours. The course of 15-20 suppositories. To increase physical performance: 1 suppository every other day – 5 suppositories, then one suppository every 72 hours, the course – up to 20 suppositories.