Description
Valokordin Pharmacodynamics
A combination drug, the action of which is caused by the pharmacological properties of its constituent components. It has a sedative and antispasmodic effect.
Phenobarbital has sedative (in low doses), hypnotic, muscle relaxant and antispasmodic effect. It helps to reduce excitation of the central nervous system and facilitates the onset of sleep, enhances the sedative effect of the other active substance.
Ethylbromisovalerianat has sedative (similar to effect of valerian) and antispasmodic effect, mainly on receptors in the mouth and nasopharynx, resulting from irritation, reduction of reflex excitability in the central nervous system and increased inhibition in the cortex and subcortical structures of the brain, as well as reducing the activity of central vasomotor centers and a direct local spasmolytic effect on smooth muscles.
Indications
As a symptomatic sedative in functional disorders of the cardiovascular system, in neurosis-like states accompanied by increased irritability, insomnia, tachycardia, states of agitation with marked vegetative manifestations.
Contraindications
Hypersensitivity to the drug components, acute hepatic porphyria, hereditary lactose intolerance, glucose-galactose malabsorption, age under 18 years (efficacy and safety have not been established), severe renal and/or hepatic dysfunction, pregnancy and breast-feeding period.
Caution
Impaired renal and/or hepatic function; concomitant use with drugs that are metabolized in the liver (see section “Interaction with other medicinal products”).
If you have one of the listed diseases/conditions, always consult your doctor before taking the drug.
Administration during pregnancy and breastfeeding
This medicine is contraindicated during pregnancy and breastfeeding because phenobarbital penetrates through the placenta and has teratogenic effect, having adverse effect on formation and further functioning of central nervous system of foetus and newborn.
Phenobarbital penetrates into breast milk. Development of physical dependence in newborn is possible.
If it is necessary to apply the drug during lactation, breastfeeding should be discontinued.
Directions for use and dosages
- Orally, before meals, with plenty of water.
- Adults take 1-2 tablets of the drug 2 times a day. In tachycardia single dose may be increased to 3 tablets.
- The maximum daily dose is 6 tablets.
- The dosage and duration of use of the drug is determined by the doctor individually for each patient.
- If necessary, please consult your doctor.
