Description
Bacteriophage Intesti Pharmacodynamics
The drug causes specific lysis of bacteria Shigella flexneri 1, 2, 3, 4, 6 serotypes, Shigella sonnei, Salmonella paratyphi A, Salmonella paratyphi B, Salmonella typhimurium, Salmonella infantis, Salmonella choleraesuis, Salmonella oranienburg, Salmonella enteritidis, enteropathogenic Escherichia coli, Proteus vulgaris, Proteus mirabilis, Enterococcus, Staphylococcus, Pseudomonas aeruginosa.
Indications
Treatment and prevention of gastrointestinal diseases caused by dysentery bacteria, Salmonella, Escherichia coli, Proteus, Enterococcus, Staphylococcus, Pseudomonas aeruginosa or their combination:
-bacterial dysentery;
-salmonellosis;
-dyspepsia;
-dysbacteriosis;
-enterocolitis, colitis.
An important condition for effective phagotherapy is prior determination of phage sensitivity of the pathogen.
Contraindications
Hypersensitivity to the drug components.
Dosage and administration
- The drug is intended for oral and rectal administration. For treatment, the drug is taken orally 4 times a day for 0.5 – 1 hour before meals from the first day of the disease within 7-10 days.
- Children of the first two days of life the drug is diluted with boiled water two times, in the absence of adverse reactions (regurgitation, skin rashes) in the future it is possible to use bacteriophage undiluted. The drug is administered by mouth 3 times a day 30 minutes before feeding. In cases of uncontrollable vomiting the drug is used in form of high enemas (through gas tube or catheter) daily. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7-10 days.
- Age Dose per administration (ml)
orally rectally
0-6 months. 5 10
6-12 months. 10-15 20
1 to 3 years 15-20 20-30
3 to 8 years 20-30 30-40
8 years and older 30-40 50-60 - In the absence of colitic syndrome, it is recommended to replace one oral intake with a single rectal administration of a single age dose of the drug in the form of an enema after bowel emptying.
- For preventive purposes, the optimal scheme of use is daily administration of a single age dose. Duration of drug administration is determined by conditions of epidemic situation.
- If after treatment no improvement occurs or symptoms worsen, or new symptoms appear, consult a doctor. Use the drug only according to the indications, the route of administration and the dosage indicated in the instructions.
