Description
Aphobazole Retard Pharmacodynamics
Aphobazole® Retard is a selective non-benzodiazepine anxiolytic.
Acting on sigma-1 receptors in nerve cells of the brain, Aphobazole® Retard stabilizes GABA/ benzodiazepine receptors and restores their sensitivity to endogenous mediators of inhibition. Aphobazol® Retard also increases the bioenergetic potential of neurons and has a neuroprotective effect: it restores and protects nerve cells.
The action of the drug is mainly realized as a combination of anxiolytic (anti-anxiety) and mild stimulant (activating) effects.
Aphobazole® Retard reduces or eliminates anxiety (anxiety, misgivings, apprehension), irritability, tension (jitteriness, tearfulness, anxiety, inability to relax, insomnia, fear), depressed mood, somatic anxiety manifestations (muscular, sensory, cardiovascular, respiratory, gastrointestinal symptoms), autonomic disturbances (dry mouth, sweating, dizziness), cognitive disturbances (difficulty concentrating, impaired memory), including those resulting from stressors. including those arising from stress disorders (adaptation disorders). It is especially indicated for individuals with predominantly asthenic personality traits such as anxious hesitancy, insecurity, increased vulnerability and emotional lability, propensity to emotional stress reactions.
Aphobazole® Retard does not cause muscle weakness, drowsiness and has no negative effect on concentration and memory. Its use does not cause addiction, drug dependence and does not lead to withdrawal syndrome.
Indications
Aphobazole® Retard is used in adults with anxiety disorders: generalized anxiety disorders, neurasthenia, adjustment disorders, in patients with various somatic diseases (bronchial asthma, irritable bowel syndrome, systemic lupus erythematosus, coronary heart disease, hypertension, arrhythmias), dermatological, oncological and other diseases; in treatment of sleep disorders associated with anxiety.
Contraindications
– Hypersensitivity to fabomotisole and / or any excipient in the drug.
– Galactose intolerance, lactase deficiency, glucose-galactose malabsorption.
– Pregnancy, breastfeeding.
– Childhood under 18 years of age.
If you have one of the above mentioned diseases, consult your physician before using the drug.
USE DURING PREGNANCY AND BREAST-FEEDING:
The use of the drug Aphobazol® Retard is contraindicated in pregnancy.
If it is necessary to use the drug during lactation, breast-feeding must be discontinued.
Before using Aphobazole® Retard if you are pregnant or think that you might be pregnant or plan to become pregnant, consult your physician.
Dosage and administration
- It is used orally.
- 1 tablet once a day, in the morning, regardless of meals.
- The duration of the course of application of the drug is 2-4 weeks.
- If after treatment no improvement occurs, or symptoms worsen or new symptoms appear, consult a doctor.
- Use the drug only according to those indications, that method of use and in those doses specified in the instructions.
