Description
Picamilon Pharmacodynamics
Nootropic, dilates cerebral blood vessels. It also has tranquilizing, psychostimulant, antiaggregant and antioxidant effects. It improves brain function through normalization of tissue metabolism and influence on cerebral circulation (increases the volumetric and linear velocity of cerebral blood flow, reduces vascular resistance by inhibiting platelet aggregation, improves microcirculation).
When a course of treatment increases physical and mental performance, reduces headache, improves memory, normalizes sleep; helps reduce or disappearance of anxiety, tension, fear; improves the condition of patients with motor and speech disorders, reduces the depressing effects of ethanol on the central nervous system. It improves blood circulation in vessels of retina and optic nerve.
Indications
In adults:
In the complex therapy of ischemic cerebrovascular disorders of mild and moderate severity, chronic cerebrovascular insufficiency, condition after craniocerebral injuries.
In the complex therapy of primary open-angle glaucoma, retinal and optic nerve diseases of vascular genesis.
In the complex treatment of vegetative dystonia syndrome, accompanied by anxiety, fear, increased irritability, emotional lability.
As part of the complex therapy for the prevention of migraine.
In the complex therapy of chronic alcoholism (to reduce asthenic, asthenoneurotic, post-psychotic, pre-recipient states, as well as alcoholic encephalopathy).
In adults and children:
In urological practice (in children over 3 years of age and in adults with urinary disorders to improve the adaptive function of the bladder (reduction of detrusor hypoxia).
Improvement of tolerance of physical and mental stress (individuals who are in stressful and extreme conditions of activity, to restore the physical performance of athletes, to increase resistance to physical and mental stress).
Contraindications .
– Hypersensitivity to sodium nicotinoyl-gamma-aminobutyrate and / or any excipient of the drug;
– Chronic renal insufficiency;
– Children under 3 years of age (in children over 3 years of age, it is used only in case of urinary disorders).
Administration during pregnancy and lactation
It is not recommended to apply during pregnancy and breast-feeding period because of lack of experience in clinical application in this category of patients.
Dosage and administration method
- Inside, regardless of the meal.
- Shake the bottle thoroughly before use.
- For easy dosing a measuring spoon with 2.5 ml and 5 ml labels is attached to the drug package.
- 5 ml of the solution contains 20 mg of the active substance.
- In case of urinary disorders, children aged 3 to 10 years should take
- 5 ml (20 mg) 2 times a day. The maximum single dose is 5 ml (20 mg), the maximum daily dose is 10 ml (40 mg). The course of treatment is 1 month.
- In children aged 11 to 15 years old take 12.5 ml (50 mg) 2 times a day in case of urinary disorders. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 25 ml (100 mg). The course of treatment is 1 month.
- In patients over 15 years of age, use 12.5 ml (50 mg) 3 times a day in case of urinary disorders. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 37.5 ml (150 mg). The course of treatment is 1 month.
- Single dose in cerebrovascular diseases – 5 ml-12.5 ml (20 mg-50 mg) 2 to 3 times a day. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 37.5 ml (150 mg). The course of treatment is 1-2 months. The course may be repeated in 5-6 months.
- In primary open angle glaucoma, 12.5 ml (50 mg) 3 times a day. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 37.5 ml (150 mg). The course of treatment is 1 month.
- In case of retinal and optic nerve diseases, intramuscular injection solution is used for the first 12 days, then depending on the condition, the drug is administered orally in
- 5 ml-12.5 ml (20 mg-50 mg) 3 times daily. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 37.5 ml (150 mg). The course of treatment is 1 month.
- For prevention of migraine attacks orally 12.5 ml (50 mg) 3 times a day. The maximum single dose is 12.5 ml (50 mg), the maximum daily dose is 37.5 ml (150 mg).
- In late-onset depression, 10 ml-50 ml (40 mg-200 mg) a day in 2-3 doses, the optimal dosage is 15 ml-30 ml (60 mg-120 mg) a day. The course of treatment is 1.5-3 months.
- As an asthenic and anxiolytic agent, 10 ml-20 ml (40 mg-80 mg) daily, if necessary up to 50 ml-75 ml (200-300 mg) daily. The course of treatment is 1-1.5 months.
- To restore the ability to work and for increased loads it is taken in the form of 15 ml – 20 ml (60-80 mg) per day for 1-1.5 months, for athletes in the same dose for 2 weeks of training period.
