Description
Panavir Pharmacodynamics
Panavir® is a purified extract of the shoots of the plant Solanum tuberosum; the main active ingredient is a hexose glycoside consisting of glucose, rhamnose, arabinose, mannose, xylose, galactose, uronic acids.
Panavir® is an antiviral and immunomodulatory agent.
It increases nonspecific resistance to various infections and promotes induction of interferon alpha and gamma by blood leukocytes.
In therapeutic doses the drug is well tolerated.
Tests showed absence of mutagenic, teratogenic, carcinogenic, allergic and embryotoxic effects. Negative effects on reproductive function and fetal development were not found in preclinical studies on laboratory animals.
It has anti-inflammatory properties in the model of experimental exudative edema.
Indications
– Herpesviral infections of various localizations (including recurrent genital herpes, herpes zoster and ophthalmoherpes);
– secondary immunodeficiencies against the background of infectious diseases;
– Cytomegalovirus infection, including in patients with habitual pregnancy failure. It is used in women with chronic viral infection and interferon deficiency at the stage of preparation for pregnancy;
– Papillomavirus infection (anogenital warts) as part of the complex therapy;
– tick-borne encephalitis to reduce the viral load and relieve neurological symptoms (anisoreflexia, decreased reflexes, painful exit points of cranial nerves, nystagmus) as part of the treatment;
– Acute respiratory infections and influenza as part of the treatment.
Contraindications .
– Hypersensitivity;
– pregnancy;
– lactation period;
– childhood.
Pregnancy and lactation:
If it is necessary to use the drug during lactation, breastfeeding should be discontinued while taking the drug.
Dosage and administration method
- Rectally.
- For treatment of herpes infections and tick-borne encephalitis use 1 suppository twice with intervals of 48 or 24 hours. If necessary, the treatment course may be repeated in 1 month.
- For the treatment of cytomegalovirus and papillomavirus infections 1 suppository is used three times during the first week at intervals of 48 hours and twice during the second week at intervals of 72 hours.
- For the treatment of acute respiratory infections and influenza, 1 suppository is used at intervals of 24 hours for 5 days.
