Description
Ximedon Pharmacodynamics
Ximedon speeds up tissue regeneration processes and shortens the period of healing of the burn surface, improves skin engraftment during autodermoplasty. It promotes normalization of the ratio between the content of fibrinogen in blood and its fibrinolytic activity, improves regional blood circulation. Normalizes the immune system, increases the phagocytic activity of T-lymphocytes and nonspecific resistance. It stimulates erythro- and leukopoiesis, cellular and humoral defense factors, has anti-inflammatory and antimicrobial effects.
Indications
In the treatment of the following diseases: deep and superficial burns (preparation of patients for autodermoplasty), long non-healing wounds, trophic ulcers, gastric and duodenal ulcers, bedsores, frostbites, purulent inflammatory diseases of soft tissues and bones, chronic osteomyelitis, streptococcal infections (angina, rye), microbial eczema, psoriasis, viral hepatitis, Lung tuberculosis, pneumonia, chronic bronchitis, chronic cystic sinusitis, salmonellosis, rheumatism, thrombophlebitis of deep veins of lower limbs, pre- and postoperative periods for prevention of purulent-inflammatory complications of postoperative wounds, especially in patients with high risk of abdominal wall (anemia, diabetes, etc.). ) and the gastrointestinal tract.
Contraindications .
Hypersensitivity. Leukemia (acute and chronic), erythremia, children under 18 years of age.
With caution:
Patients with diabetes should have their glucose tolerance determined more frequently, due to a possible decrease in the need for insulin.
Pregnancy and lactation:
Use of the drug is indicated only when the anticipated benefit to the mother exceeds the potential risk to the fetus.
During the treatment it is necessary to decide on stopping of breast feeding.
Dosage and administration
- It is used orally before meals.
- If deep and superficial burns (preparing patients for autodermoplasty) – 0.5 g 3 times a day for 20 days. During skin-plastic operations the drug is prescribed before and after surgery for 10 days.
- With long-duration nonhealing wounds, trophic ulcers, bedsores – 0.5 g 3 times a day for 25-30 days.
- With gastric ulcer and duodenal ulcer – 0.5 g 2 times a day for a course of 12 days.
- With frostbite – 0.25-0.5 g 3-4 times a day for 2-5 weeks.
- When pyo-inflammatory diseases of soft tissue and bone – 0.5 g 4 times a day for 10-30 days.
- In chronic osteomyelitis – before and after surgery to 0.5 g 4 times a day for 20-25 days.
- Repeated courses of treatment are carried out after 6 months for 1.5 years.
- With angina, rye – 0.5 g 3 times a day for 7-10 days.
- When microbial eczema – 0.5 g 3 times a day for 10 days.
- With psoriasis – 0.5 g 3 times a day for 2-3 weeks.
- With viral hepatitis B and C – 0.5 g 3 times a day for 10 days.
- With pulmonary tuberculosis – 0.5 g 4 times a day for 2 months.
- With pneumonia and chronic bronchitis – 0.5 g 4 times a day for 18-21 days.
- With chronic cystic sinusitis – 0.25-0.5 g 4 times a day for 1 month.
- With salmonellosis – 0.5 g 3 times a day for 7 days.
- With rheumatism – 0.5 g 3 times a day for 3-4 weeks.
- In pre- and postoperative periods to prevent pyoinflammatory complications of postoperative wounds, especially in patients with high risk of abdominal wall suture failure (anemia, diabetes, etc.) and gastrointestinal tract – 0.5 g 4 times a day for 10-20 days (from the first day after surgery or in preoperative period 3-5 days and then from the first day after surgery).
